ID A0A346A5M5_9SPHI Unreviewed; 603 AA. AC A0A346A5M5; DT 07-NOV-2018, integrated into UniProtKB/TrEMBL. DT 07-NOV-2018, sequence version 1. DT 13-SEP-2023, entry version 12. DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418}; DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418}; DE Flags: Fragment; OS Sphingobacterium caeni. OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales; OC Sphingobacteriaceae; Sphingobacterium. OX NCBI_TaxID=1204554 {ECO:0000313|EMBL:AXK90320.1}; RN [1] {ECO:0000313|EMBL:AXK90320.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CCTCC AB 2012020 {ECO:0000313|EMBL:AXK90320.1}; RA Cheng J.F., Li Y.H.; RT "Comparison of rpoB sequences of Sphingobacterium species."; RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550}; CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family. CC {ECO:0000256|RuleBase:RU000434}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MH229981; AXK90320.1; -; Genomic_DNA. DR AlphaFoldDB; A0A346A5M5; -. DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC. DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro. DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro. DR Gene3D; 2.40.50.100; -; 1. DR Gene3D; 3.90.1100.10; -; 1. DR Gene3D; 2.30.150.10; DNA-directed RNA polymerase, beta subunit, external 1 domain; 1. DR Gene3D; 3.90.1110.10; RNA polymerase Rpb2, domain 2; 2. DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf. DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1. DR InterPro; IPR015712; DNA-dir_RNA_pol_su2. DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom. DR InterPro; IPR010243; RNA_pol_bsu_bac. DR InterPro; IPR007642; RNA_pol_Rpb2_2. DR InterPro; IPR037034; RNA_pol_Rpb2_2_sf. DR InterPro; IPR007645; RNA_pol_Rpb2_3. DR NCBIfam; TIGR02013; rpoB; 1. DR PANTHER; PTHR20856; DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; 1. DR PANTHER; PTHR20856:SF20; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; 1. DR Pfam; PF04561; RNA_pol_Rpb2_2; 2. DR Pfam; PF04565; RNA_pol_Rpb2_3; 1. DR Pfam; PF10385; RNA_pol_Rpb2_45; 1. DR Pfam; PF00562; RNA_pol_Rpb2_6; 1. DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1. PE 3: Inferred from homology; KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478, KW ECO:0000313|EMBL:AXK90320.1}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 5..49 FT /note="RNA polymerase Rpb2" FT /evidence="ECO:0000259|Pfam:PF04561" FT DOMAIN 128..246 FT /note="RNA polymerase Rpb2" FT /evidence="ECO:0000259|Pfam:PF04561" FT DOMAIN 305..373 FT /note="RNA polymerase Rpb2" FT /evidence="ECO:0000259|Pfam:PF04565" FT DOMAIN 383..450 FT /note="DNA-directed RNA polymerase beta subunit external 1" FT /evidence="ECO:0000259|Pfam:PF10385" FT DOMAIN 512..603 FT /note="DNA-directed RNA polymerase subunit 2 hybrid- FT binding" FT /evidence="ECO:0000259|Pfam:PF00562" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AXK90320.1" FT NON_TER 603 FT /evidence="ECO:0000313|EMBL:AXK90320.1" SQ SEQUENCE 603 AA; 68153 MW; CFA45A6CD93A7D22 CRC64; VIPFKGSWIE FATDVNNVMY AYIDRKKKFP VTTLLRAIGY DSDKDILELF DLADEVKVSK SGLKKYVGRR LAARVLKKWV EDFVDEDTGE VVSIDRNEII LERETVLEED HIDLIIEAGV KSIILAKDDE SNNADYSIIY NTLQKDTSNS EKEAVEHIYR QLRNAEPPDE ETARGIIDRL FFSDKRYDLG DVGRYRINRK LKLGTPDDTK VLTREDIIAI VKYLINLINS KAEVDDIDHL SNRRVRTVGE QLYAQFGVGL SRMARTIRER MNIRDNEVFT PTDLINARTL SSVINSFFGT NQLSQFMDQT NPLAEITHKR RLSALGPGGL SRERAGFEVR DVHYTHYGRL CTIETPEGPN IGLISSLAVH AKINHLGFIE TPYRKVKDGV VVVDEPVVYL SAEDEDGKTI AQANALYDDK GNFEDAKVKA RYEGDFPIIE PNMLDYMDVA PNQITSIAAS LIPFLEHDDA NRALMGSNMQ RQAVPVLRPQ APIVGTGLEG RVAKDSRTLI NAEGHGVVEY VDADEIKIRY DRNDDDRLVS FDDDVKTYKL IKFKKTNQNT CMNLKPIVKK GQRVEPGQVL CEGYATENGE LALGRNLKVA FMP //