ID A0A345AMC6_MACMU Unreviewed; 705 AA.
AC A0A345AMC6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 29-MAY-2024, entry version 16.
DE SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|EMBL:AXF37597.1};
GN Name=CEACAM5 {ECO:0000313|EMBL:AXF37597.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AXF37597.1};
RN [1] {ECO:0000313|EMBL:AXF37597.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=29858229; DOI=10.15252/embj.201798665;
RA Moonens K., Hamway Y., Neddermann M., Reschke M., Tegtmeyer N., Kruse T.,
RA Kammerer R., Mejias-Luque R., Singer B.B., Backert S., Gerhard M.,
RA Remaut H.;
RT "Helicobacter pylori adhesin HopQ disrupts trans dimerization
RT in human CEACAMs.";
RL EMBO J. 37:e98665-e98665(2018).
RN [2] {ECO:0000313|EMBL:AXF37597.1}
RP NUCLEOTIDE SEQUENCE.
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR EMBL; MG874671; AXF37597.1; -; mRNA.
DR AlphaFoldDB; A0A345AMC6; -.
DR GO; GO:0009986; C:cell surface; IEA:TreeGrafter.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:1990782; F:protein tyrosine kinase binding; IEA:TreeGrafter.
DR GO; GO:0002682; P:regulation of immune system process; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:TreeGrafter.
DR CDD; cd20948; IgC2_CEACAM5-like; 3.
DR CDD; cd05740; IgI_hCEACAM_2_4_6_like; 3.
DR CDD; cd05774; IgV_CEACAM_D1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR PANTHER; PTHR44427:SF20; CEA CELL ADHESION MOLECULE 8; 1.
DR Pfam; PF13895; Ig_2; 3.
DR Pfam; PF13927; Ig_3; 3.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 2: Evidence at transcript level;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..705
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017005520"
FT DOMAIN 145..232
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..314
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 323..410
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 418..492
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 501..588
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 593..675
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 705 AA; 77547 MW; 80DA3D0E93F9ADD0 CRC64;
MGSPSAPLHR WCIPWQTLLL TASLLTFWNP PTTAQLTIES RPFNVAEGKE VLLLAHNVSQ
NLFGYIWYKG ERVDASRRIG SCVIRTQQIT PGPAHSGRET IDFNASLLIQ NVTQNDTGSY
TIQVIKEDLV NEEATGQFRV YPELPKPYIS SNNSNPVEDK DAVALTCEPE TQDTTYLWWV
NNQSLPVSPR LELSSDNRTL TVFNIPRNDT TSYKCETQNP VSVRRSDPVT LNVLYGPDAP
TISPLNTPYR AGENLNLTCH AASNPTAQYF WFVNGTFQQS TQELFIPNIT VNNSGSYMCQ
AHNSATGLNR TTVTAITVYA ELPKPYITSN NSNPIEDKDA VTLTCEPETQ DTTYLWWVNN
QSLSVSSRLE LSNDNRTLTV FNIPRNDTTF YECETQNPVS VRRSDPVTLN VLYGPDAPTI
SPLNTPYRAG ENLNLSCHAA SNPAAQYSWF VNGTFQQSTQ ELFIPNITVN NSGSYMCQAH
NSATGLNRTT VTAITVYVEL PKPYISSNNS NPIEDKDAVT LTCEPVAENT TYLWWVNNQS
LSVSPRLQLS NGNRILTLLS VTRNDTGPYE CGIQNSESAK RSDPVTLNVT YGPDTPIISP
PDLSYRSGAN LNLSCHSDSN PSPQYSWLIN GTLRQHTQVL FISKITSNNN GAYACFVSNL
ATGRNNSIVK NISVSSGDSA PGSSGLSARA TVGIIIGMLV GVALM
//