ID   A0A2Y9G2X7_NEOSC        Unreviewed;       753 AA.
AC   A0A2Y9G2X7;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   11-DEC-2019, entry version 7.
DE   SubName: Full=probable tRNA (Uracil-O(2)-)-methyltransferase {ECO:0000313|RefSeq:XP_021533382.1};
GN   Name=TRMT44 {ECO:0000313|RefSeq:XP_021533382.1};
OS   Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Phocidae; Neomonachus.
OX   NCBI_TaxID=29088 {ECO:0000313|Proteomes:UP000248481, ECO:0000313|RefSeq:XP_021533382.1};
RN   [1] {ECO:0000313|RefSeq:XP_021533382.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_021533382.1};
RG   RefSeq;
RL   Submitted (JUN-2018) to UniProtKB.
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DR   RefSeq; XP_021533382.1; XM_021677707.1.
DR   Proteomes; UP000248481; Genome assembly.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   InterPro; IPR011671; tRNA_uracil_MeTrfase.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR21210; PTHR21210; 1.
DR   Pfam; PF07757; AdoMet_MTase; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Methyltransferase {ECO:0000313|RefSeq:XP_021533382.1};
KW   Transferase {ECO:0000313|RefSeq:XP_021533382.1};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT   DOMAIN          708..738
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   ZN_FING         708..738
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT   REGION          54..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          529..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        537..551
FT                   /note="Pro-rich"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   753 AA;  83074 MW;  016D1BBCC93FCD66 CRC64;
     MAEVGRAAVR DPGALLPGGF WAAVAVWLER PQVANKRLCG VRLDARRSVG FPRAEACGHS
     PITGPQQEER AAARPCLRSP SGGLGPGPST GPELGTAGRG PEESQPRLPQ GEDPREAAAA
     AQLAGCPGQP GKAGVGEGDF PASDLDSLWD AFSRSLAGGN PEMLAFLTGS RAGSQPEAPS
     ELDVVLRTVI PKTGPHCPLA APRREIVVQD VLNGTVTFLP LEEDDRGNVK VEMSNVYQVR
     LSQSQEEWFI SILIFCPEKW HSDGIVYPKP TWLVEELLAR LARWSVESKR SGFKSTLSLI
     SIIKYSKTYQ MLKEKYKDMV KVWPEVTDPE KFVYEDVAIA AYLLILWEEE RAERGLTAKQ
     SFVDLGCGNG LLVHILSTEG HPGRGIDVRR RKIWDTYGPQ TCLEEGAITP NDKNLFPDVD
     WLIGNHSDEL TPWIPVIAAR SSYGCRFFVL PCCFFGFTGK YSRRQSRKTQ YREYLDFIME
     VGLACGFHVE EDCLRIPSTK RVCLIGKSRT YSPAGEGSMD EQRTQYINSR RGRPMSPPGK
     APAPPPPRAA VGRAGHPDGP QAPDAEAAEG GAEARANQLW LSGFQPREKA ERVRNCATLP
     RDFIDQVVLQ VAHLLLDGEQ LNTGSAPSSS SKAWNRGGSL SLAEVAHKLD RGMLQRLKRE
     CGGLQTLLRN NHQVFEVLNG SVHIRDWREE KPHRQQCPEA KRKLFSEAFK TRICWFFSHH
     PDGCVLPSDG CPFAHGPAEL RPPQTPKRQK QVL
//