ID   A0A2Y9ENC9_PHYCD        Unreviewed;       578 AA.
AC   A0A2Y9ENC9;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   07-NOV-2018, entry version 3.
DE   SubName: Full=zinc finger protein with KRAB and SCAN domains 8 {ECO:0000313|RefSeq:XP_007105906.1};
GN   Name=ZKSCAN8 {ECO:0000313|RefSeq:XP_007105906.1};
OS   Physeter catodon (Sperm whale) (Physeter macrocephalus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;
OC   Odontoceti; Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007105906.1};
RN   [1] {ECO:0000313|RefSeq:XP_007105906.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007105906.1};
RG   RefSeq;
RL   Submitted (JUN-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
CC       ProRule:PRU00187, ECO:0000256|SAAS:SAAS00921827}.
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DR   RefSeq; XP_007105906.1; XM_007105844.1.
DR   RefSeq; XP_007105907.1; XM_007105845.1.
DR   GeneID; 102991658; -.
DR   Proteomes; UP000248484; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   CDD; cd07936; SCAN; 1.
DR   Gene3D; 1.10.4020.10; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   InterPro; IPR003309; SCAN_dom.
DR   InterPro; IPR038269; SCAN_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 9.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF109640; SSF109640; 1.
DR   SUPFAM; SSF57667; SSF57667; 5.
DR   PROSITE; PS50805; KRAB; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000248484};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00926372};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187,
KW   ECO:0000256|SAAS:SAAS00921821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Repeat {ECO:0000256|SAAS:SAAS00926344};
KW   Transcription {ECO:0000256|SAAS:SAAS00921833};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00921823};
KW   Zinc {ECO:0000256|SAAS:SAAS00926345};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042,
KW   ECO:0000256|SAAS:SAAS00926370}.
FT   DOMAIN       51    133       SCAN box. {ECO:0000259|PROSITE:PS50804}.
FT   DOMAIN      220    316       KRAB. {ECO:0000259|PROSITE:PS50805}.
FT   DOMAIN      322    349       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      350    377       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      378    405       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      406    433       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      434    461       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      462    489       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      490    517       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      518    545       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      546    573       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
SQ   SEQUENCE   578 AA;  65362 MW;  191804BCCE484FB9 CRC64;
     MAAESRKSLA PSPPDQAPEE DLVIIKVEED HGWDQESSLH ESNPPGQELF RLRFRKLCYQ
     ETLGPREALI QLRALCHQWL RPDLNTKEQI LELLVLEQFL TILPEELQTL VKEHQLENGE
     EVVTLLEDLE RQIDILGRPV PARAHGHRVL WEEVMHSKSA PEPADTQLQP VATQHKSPVL
     QGPQDRAISA SQSPTPSQKG SPRDQEMTAT LLTAGFQTLE KIEDMAVSLI REEWLLDSSQ
     KDLSRDSRPE NYRNMFSLGG ETRNENRELA SKQVISAGIQ PHGETAAKCN GDVIGGLEHG
     EARDLLGTLE RQRGNPTQER RHKCDECGKS FAQSSGLVRH WRIHTGEKPY QCNVCGKAFS
     YRSALLSHQD IHNKVKRYHC KECGKAFSQN TGLILHQRIH TGEKPYQCNQ CGKAFSQSAG
     LILHQRIHSG ERPYECNECG KAFSHSSHLI GHQRIHTGEK PYECDECGKT FRRSSHLIGH
     QRSHTGEKPY KCNECGRAFS QKSGLIEHQR IHTGERPYKC KECGKAFNGN TGLIQHLRIH
     TGEKPYQCNE CGKAFIQRSS LIRHQRIHSG EKSESTGV
//