ID A0A2W5SZS4_9MICO Unreviewed; 114 AA. AC A0A2W5SZS4; DT 12-SEP-2018, integrated into UniProtKB/TrEMBL. DT 12-SEP-2018, sequence version 1. DT 12-AUG-2020, entry version 6. DE RecName: Full=mRNA interferase {ECO:0000256|PIRNR:PIRNR033490}; DE EC=3.1.-.- {ECO:0000256|PIRNR:PIRNR033490}; GN ORFNames=DI534_12425 {ECO:0000313|EMBL:PZQ88407.1}; OS Leifsonia xyli. OC Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae; Leifsonia. OX NCBI_TaxID=1575 {ECO:0000313|EMBL:PZQ88407.1, ECO:0000313|Proteomes:UP000249071}; RN [1] {ECO:0000313|EMBL:PZQ88407.1, ECO:0000313|Proteomes:UP000249071} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S2_003_000_R2_12 {ECO:0000313|EMBL:PZQ88407.1}; RA Brooks B., Olm M.R., Firek B.A., Baker R., Thomas B.C., Morowitz M.J., RA Banfield J.F.; RT "Infants hospitalized years apart are colonized by the same room-sourced RT microbial strains."; RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Toxic component of a type II toxin-antitoxin (TA) system. CC {ECO:0000256|PIRNR:PIRNR033490}. CC -!- SIMILARITY: Belongs to the PemK/MazF family. CC {ECO:0000256|ARBA:ARBA00007521, ECO:0000256|PIRNR:PIRNR033490}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PZQ88407.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QFQR01000006; PZQ88407.1; -; Genomic_DNA. DR Proteomes; UP000249071; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR Gene3D; 2.30.30.110; -; 1. DR InterPro; IPR003477; PemK-like. DR InterPro; IPR011067; Plasmid_toxin/cell-grow_inhib. DR PANTHER; PTHR33988; PTHR33988; 1. DR Pfam; PF02452; PemK_toxin; 1. DR PIRSF; PIRSF033490; MazF; 1. PE 3: Inferred from homology; KW Endonuclease {ECO:0000256|PIRNR:PIRNR033490}; KW Hydrolase {ECO:0000256|PIRNR:PIRNR033490}; KW Nuclease {ECO:0000256|PIRNR:PIRNR033490}; KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}. SQ SEQUENCE 114 AA; 11907 MW; F0C494D508FB7BCD CRC64; MRRGAIVVVD FDPIVGSEAA RSRPAVIVSN NTANAAATRT GGVVTVVPLT GNTARVHPFQ VLLPAGATGL PRDSKAQAEQ VRTVSVARIR SAAGWATTEL MRELDAALRL HLGL //