ID A0A2V5UXM4_UNCVE Unreviewed; 353 AA. AC A0A2V5UXM4; DT 12-SEP-2018, integrated into UniProtKB/TrEMBL. DT 12-SEP-2018, sequence version 1. DT 13-SEP-2023, entry version 13. DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:PYJ66547.1}; DE Flags: Fragment; GN ORFNames=DME78_04605 {ECO:0000313|EMBL:PYJ66547.1}; OS Verrucomicrobiota bacterium. OC Bacteria; Verrucomicrobiota. OX NCBI_TaxID=2026799 {ECO:0000313|EMBL:PYJ66547.1, ECO:0000313|Proteomes:UP000248105}; RN [1] {ECO:0000313|EMBL:PYJ66547.1, ECO:0000313|Proteomes:UP000248105} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AV61 {ECO:0000313|EMBL:PYJ66547.1}; RX PubMed=29899444; DOI=10.1038/s41586-018-0207-y; RA Crits-Christoph A., Diamond S., Butterfield C.N., Thomas B.C., RA Banfield J.F.; RT "Novel soil bacteria possess diverse genes for secondary metabolite RT biosynthesis."; RL Nature 558:440-444(2018). CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PYJ66547.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QHOC01000075; PYJ66547.1; -; Genomic_DNA. DR AlphaFoldDB; A0A2V5UXM4; -. DR Proteomes; UP000248105; Unassembled WGS sequence. DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW. DR CDD; cd02440; AdoMet_MTases; 1. DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1. DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1. DR InterPro; IPR025714; Methyltranfer_dom. DR InterPro; IPR020803; PKS_MeTfrase. DR InterPro; IPR029063; SAM-dependent_MTases_sf. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR PANTHER; PTHR45128:SF2; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1. DR PANTHER; PTHR45128; METHYLTRANSFERASE TYPE 11; 1. DR Pfam; PF13847; Methyltransf_31; 1. DR SMART; SM00828; PKS_MT; 1. DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1. DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1. PE 4: Predicted; KW Methyltransferase {ECO:0000313|EMBL:PYJ66547.1}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PYJ66547.1}. FT DOMAIN 156..353 FT /note="Polyketide synthase methyltransferase" FT /evidence="ECO:0000259|SMART:SM00828" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:PYJ66547.1" SQ SEQUENCE 353 AA; 38479 MW; 042982FD527B0F32 CRC64; ATIDAARQEE FVGKVVEQIS GTMTTLLGAV GDRLGLFKNL AAEGPATSAE LASRTKLNER YLREWLGGMA TAGYLSYDGS TKRFSLPAEH ASVLAHENGP FFIGGIYQML PAQAGVFDQV VSAFRNGGGV SQSQYNDMMW DGLERFTSTW FENLLLQQWI PAMPDVKAHL ERGSDVADVG CGRGRGLIKL AEAFPRSRYV GYDNFGPTVV RATANARDAG VSGRVRFEER DVSKGLPAQF DVITTFDVVH DAVDPLQLLQ SIRRALRPGG IYVCLDINCS EKLEENANPL GAMFHGVSVF YCMTTSLANH GAGLGTLGFH EAKVRELCEK AGFSSVRRVP LENPFNNLYE AKP //