ID A0A2T9WS03_9CREN Unreviewed; 322 AA. AC A0A2T9WS03; DT 18-JUL-2018, integrated into UniProtKB/TrEMBL. DT 18-JUL-2018, sequence version 1. DT 02-JUN-2021, entry version 16. DE RecName: Full=DNA repair and recombination protein RadA {ECO:0000256|ARBA:ARBA00018144, ECO:0000256|HAMAP-Rule:MF_00348}; GN Name=radA {ECO:0000256|HAMAP-Rule:MF_00348}; GN ORFNames=DDW09_01920 {ECO:0000313|EMBL:PVU70634.1}; OS Sulfolobus sp. SCGC AB-777_L09. OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; OC Sulfolobus; unclassified Sulfolobus. OX NCBI_TaxID=1987492 {ECO:0000313|EMBL:PVU70634.1, ECO:0000313|Proteomes:UP000245548}; RN [1] {ECO:0000313|EMBL:PVU70634.1, ECO:0000313|Proteomes:UP000245548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SCGC AB-777_L09 {ECO:0000313|EMBL:PVU70634.1}; RX PubMed=26341207; DOI=10.1128/AEM.01539-15; RA Munson-McGee J.H., Field E.K., Bateson M., Rooney C., Stepanauskas R., RA Young M.J.; RT "Nanoarchaeota, Their Sulfolobales Host, and Nanoarchaeota Virus RT Distribution across Yellowstone National Park Hot Springs."; RL Appl. Environ. Microbiol. 81:7860-7868(2015). CC -!- FUNCTION: Involved in DNA repair and in homologous recombination. Binds CC and assemble on single-stranded DNA to form a nucleoprotein filament. CC Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand CC exchange between homologous DNA molecules. {ECO:0000256|HAMAP- CC Rule:MF_00348, ECO:0000256|PIRNR:PIRNR005856}. CC -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. CC {ECO:0000256|ARBA:ARBA00008050, ECO:0000256|HAMAP-Rule:MF_00348, CC ECO:0000256|PIRNR:PIRNR005856}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PVU70634.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; QEFI01000009; PVU70634.1; -; Genomic_DNA. DR Proteomes; UP000245548; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0008094; F:ATPase activity, acting on DNA; IEA:UniProtKB-UniRule. DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule. DR CDD; cd01123; Rad51_DMC1_radA; 1. DR HAMAP; MF_00348; RadA_arch; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C. DR InterPro; IPR011938; DNA_recomb/repair_RadA. DR InterPro; IPR016467; DNA_recomb/repair_RecA-like. DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR033925; Rad51_DMC1_RadA. DR InterPro; IPR020588; RecA_ATP-bd. DR InterPro; IPR020587; RecA_monomer-monomer_interface. DR Pfam; PF08423; Rad51; 1. DR PIRSF; PIRSF005856; Rad51; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF47794; SSF47794; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR02236; recomb_radA; 1. DR PROSITE; PS50162; RECA_2; 1. DR PROSITE; PS50163; RECA_3; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP- KW Rule:MF_00348}; KW DNA damage {ECO:0000256|HAMAP-Rule:MF_00348, KW ECO:0000256|PIRNR:PIRNR005856}; KW DNA recombination {ECO:0000256|HAMAP-Rule:MF_00348, KW ECO:0000256|PIRNR:PIRNR005856}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP- KW Rule:MF_00348}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP- KW Rule:MF_00348}; Reference proteome {ECO:0000313|Proteomes:UP000245548}. FT DOMAIN 83..255 FT /note="RECA_2" FT /evidence="ECO:0000259|PROSITE:PS50162" FT DOMAIN 260..322 FT /note="RECA_3" FT /evidence="ECO:0000259|PROSITE:PS50163" FT NP_BIND 112..119 FT /note="ATP" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00348" SQ SEQUENCE 322 AA; 35442 MW; 456E4BBA5A621D7E CRC64; MSDGNNKKVK SLSDLPGIGQ AILNKLVDAG YSTLESVAVA SPQDLSVAAG IPLTTAQRII KEAREALDIR FKTALEVKKE RLNTKKITTG SQALDGLLGG GIETRTMTEF FGEFGSGKTQ LCHQLSVNVQ LPFEKGGLNG KAVYIDTEGT FRWERIEAMA KALGLDVDNA MSNIYYMRAI NSDHQMAIVD DLQELISKDP AIKLVIVDSV TSHFRAEYPG RENLAVRQQK MNKHLHQLVR LAEMYDLAVI ITNQVMARPD MFYGDPTVAV GGHTLYHVPG IRVQLKKSRG NKRIARIVDA PHLPEGEVVF AITEEGVRDA EE //