ID   A0A2T7EFG0_9POAL        Unreviewed;       501 AA.
AC   A0A2T7EFG0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JUL-2024, entry version 20.
DE   RecName: Full=Trans-cinnamate 4-monooxygenase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GQ55_3G324500 {ECO:0000313|EMBL:PUZ66562.1};
OS   Panicum hallii var. hallii.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Panicodae; Paniceae; Panicinae; Panicum;
OC   Panicum sect. Panicum.
OX   NCBI_TaxID=1504633 {ECO:0000313|EMBL:PUZ66562.1, ECO:0000313|Proteomes:UP000244336};
RN   [1] {ECO:0000313|EMBL:PUZ66562.1, ECO:0000313|Proteomes:UP000244336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HAL2 {ECO:0000313|Proteomes:UP000244336};
RA   Lovell J., Jenkins J., Lowry D., Mamidi S., Sreedasyam A., Weng X.,
RA   Barry K., Bonette J., Campitelli B., Daum C., Gordon S., Gould B.,
RA   Lipzen A., MacQueen A., Palacio-Mejia J., Plott C., Shakirov E., Shu S.,
RA   Yoshinaga Y., Zane M., Rokhsar D., Grimwood J., Schmutz J., Juenger T.;
RT   "WGS assembly of Panicum hallii var. hallii HAL2.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971,
CC         ECO:0000256|PIRSR:PIRSR602401-1};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; CM009751; PUZ66562.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T7EFG0; -.
DR   STRING; 1504633.A0A2T7EFG0; -.
DR   EnsemblPlants; PUZ66562; PUZ66562; GQ55_3G324500.
DR   Gramene; PUZ66562; PUZ66562; GQ55_3G324500.
DR   Proteomes; UP000244336; Chromosome 3.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:TreeGrafter.
DR   GO; GO:0009808; P:lignin metabolic process; IEA:TreeGrafter.
DR   CDD; cd11074; CYP73; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR47948; TRANS-CINNAMATE 4-MONOOXYGENASE; 1.
DR   PANTHER; PTHR47948:SF1; TRANS-CINNAMATE 4-MONOOXYGENASE; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|PIRSR:PIRSR602401-1, ECO:0000256|RuleBase:RU000461};
KW   Iron {ECO:0000256|PIRSR:PIRSR602401-1, ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR602401-1,
KW   ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244336}.
FT   BINDING         443
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602401-1"
SQ   SEQUENCE   501 AA;  56991 MW;  951B6FDA3D8027EC CRC64;
     MDLALLEKAL LGLFAAAVLA IAVAKLTGKR LRLPPGPAGA PVVGNWLQVG DDLNHRNLMA
     LAKRFGDIFL LRMGVRNLVV VSTPELAKEV LHTQGVEFGS RTRNVVFDIF TGKGQDMVFT
     VYGDHWRKMR RIMTVPFFTN KVVAQNRAGW EEEARLVVED VRRDPRAAAE GVVIRKRLQL
     MMYNDMFRIM FDRRFESEQD PLFNKLKALN AERSRLSQSF EYNYGDFIPV LRPFLRGYLN
     RCHDLKTRRM KVFEDNFVEE RKKVMAQTGE IRCAMDHILE AERKGEINHD NVLYIVENIN
     VAAIETTLWS IEWGIAELVN HPATQSKLRE EITSVLGAGV AVTEPDLERL PYLQAVVKET
     LRLRMAIPLL VPHMNLNDGK LHGYDIPAES KILVNAWFLA NDPKRWVKPE EFRPERFLEE
     EKAVEAHGND FRFVPFGVGR RSCPGIILAL PIIGITLGRL VQNFQLLPPP GQDKVDTTEK
     PGQFSNQIAK HATIVCKPLE A
//