ID A0A2S0MTG5_9RHOB Unreviewed; 318 AA. AC A0A2S0MTG5; DT 18-JUL-2018, integrated into UniProtKB/TrEMBL. DT 18-JUL-2018, sequence version 1. DT 29-SEP-2021, entry version 13. DE RecName: Full=Tyrosine recombinase XerC {ECO:0000256|HAMAP-Rule:MF_01808}; GN Name=xerC {ECO:0000256|HAMAP-Rule:MF_01808}; GN ORFNames=C6Y53_16550 {ECO:0000313|EMBL:AVO39162.1}; OS Pukyongiella litopenaei. OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales; OC Rhodobacteraceae; Pukyongiella. OX NCBI_TaxID=2605946 {ECO:0000313|EMBL:AVO39162.1, ECO:0000313|Proteomes:UP000237655}; RN [1] {ECO:0000313|Proteomes:UP000237655} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SH-1 {ECO:0000313|Proteomes:UP000237655}; RA Kim Y.-S., Kim S.-E., Kim K.-H.; RT "Genomic analysis of the strain SH-1 isolated from shrimp intestine."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing CC the cutting and rejoining of the recombining DNA molecules. The XerC- CC XerD complex is essential to convert dimers of the bacterial chromosome CC into monomers to permit their segregation at cell division. It also CC contributes to the segregational stability of plasmids. CC {ECO:0000256|HAMAP-Rule:MF_01808}. CC -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two CC molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP- CC Rule:MF_01808}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, CC ECO:0000256|HAMAP-Rule:MF_01808}. CC -!- SIMILARITY: Belongs to the 'phage' integrase family. XerC subfamily. CC {ECO:0000256|HAMAP-Rule:MF_01808}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP027665; AVO39162.1; -; Genomic_DNA. DR EnsemblBacteria; AVO39162; AVO39162; C6Y53_16550. DR KEGG; thas:C6Y53_16550; -. DR Proteomes; UP000237655; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule. DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.150.130; -; 1. DR Gene3D; 1.10.443.10; -; 1. DR HAMAP; MF_01808; Recomb_XerC_XerD; 1. DR InterPro; IPR044068; CB. DR InterPro; IPR011010; DNA_brk_join_enz. DR InterPro; IPR013762; Integrase-like_cat_sf. DR InterPro; IPR002104; Integrase_catalytic. DR InterPro; IPR010998; Integrase_recombinase_N. DR InterPro; IPR004107; Integrase_SAM-like_N. DR InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD. DR Pfam; PF02899; Phage_int_SAM_1; 1. DR Pfam; PF00589; Phage_integrase; 1. DR SUPFAM; SSF56349; SSF56349; 1. DR PROSITE; PS51900; CB; 1. DR PROSITE; PS51898; TYR_RECOMBINASE; 1. PE 3: Inferred from homology; KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP- KW Rule:MF_01808}; KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP- KW Rule:MF_01808}; KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP- KW Rule:MF_01808}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01808}; KW DNA integration {ECO:0000256|ARBA:ARBA00022908, ECO:0000256|HAMAP- KW Rule:MF_01808}; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP- KW Rule:MF_01808}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP- KW Rule:MF_01808}; Reference proteome {ECO:0000313|Proteomes:UP000237655}. FT DOMAIN 5..90 FT /note="Core-binding (CB)" FT /evidence="ECO:0000259|PROSITE:PS51900" FT DOMAIN 111..304 FT /note="Tyr recombinase" FT /evidence="ECO:0000259|PROSITE:PS51898" FT ACT_SITE 154 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" FT ACT_SITE 178 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" FT ACT_SITE 256 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" FT ACT_SITE 259 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" FT ACT_SITE 282 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" FT ACT_SITE 291 FT /note="O-(3'-phospho-DNA)-tyrosine intermediate" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01808" SQ SEQUENCE 318 AA; 35017 MW; 82A1A40C6D76AC6A CRC64; MTAPAHPHDW IAQFLEAQAA EMGAATNTLL AYGRDLKDFA EWLDRQGSGF AQADRDAVER YLIHCDAQGL ARSTRARRLS AIRQLFHFTF DEGWRGDNPA IQISGPGRDK RLPGTLAVDE VDRLLEAARH TGRAPADRLR NSCLMELLYA TGMRVSELVA LPVSTTRGDP RMLLIRGKGG RERMVPLSPP ARAALADWLT ARDETEADRE AKGHAPSRFL FPSRSSAGHL TRHRFYLLIK ELAVAGGVDP SKVSPHKLRH AFATHLLANG ADLRSIQTLL GHADLATTEI YTHVLDARLA ELVLEHHPLA RDSDGDGS //