ID A0A2R9AV73_PANPA Unreviewed; 478 AA. AC A0A2R9AV73; DT 20-JUN-2018, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 1. DT 19-JAN-2022, entry version 21. DE SubName: Full=Scavenger receptor class B member 2 {ECO:0000313|Ensembl:ENSPPAP00000021201}; GN Name=SCARB2 {ECO:0000313|Ensembl:ENSPPAP00000021201}; OS Pan paniscus (Pygmy chimpanzee) (Bonobo). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Pan. OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000021201, ECO:0000313|Proteomes:UP000240080}; RN [1] {ECO:0000313|Ensembl:ENSPPAP00000021201, ECO:0000313|Proteomes:UP000240080} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=22722832; DOI=10.1038/nature11128; RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B., RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C., RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J., RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M., RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L., RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E., RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J., RA Paabo S.; RT "The bonobo genome compared with the chimpanzee and human genomes."; RL Nature 486:527-531(2012). RN [2] {ECO:0000313|Ensembl:ENSPPAP00000021201} RP IDENTIFICATION. RG Ensembl; RL Submitted (APR-2018) to UniProtKB. CC -!- SIMILARITY: Belongs to the CD36 family. CC {ECO:0000256|ARBA:ARBA00010532}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJFE02115212; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AJFE02115213; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AJFE02115214; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_003832339.1; XM_003832291.2. DR STRING; 9597.XP_003832339.1; -. DR Ensembl; ENSPPAT00000044001; ENSPPAP00000021201; ENSPPAG00000033699. DR GeneID; 100991271; -. DR KEGG; pps:100991271; -. DR CTD; 950; -. DR GeneTree; ENSGT00940000153372; -. DR OMA; GQQNYKD; -. DR Proteomes; UP000240080; Chromosome 4. DR GO; GO:0030666; C:endocytic vesicle membrane; IEA:Ensembl. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0043202; C:lysosomal lumen; IEA:Ensembl. DR GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl. DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl. DR GO; GO:0051087; F:chaperone binding; IEA:Ensembl. DR GO; GO:0015485; F:cholesterol binding; IEA:Ensembl. DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl. DR GO; GO:0031210; F:phosphatidylcholine binding; IEA:Ensembl. DR GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl. DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl. DR GO; GO:0005044; F:scavenger receptor activity; IEA:Ensembl. DR GO; GO:0015917; P:aminophospholipid transport; IEA:Ensembl. DR GO; GO:0010467; P:gene expression; IEA:Ensembl. DR GO; GO:0006622; P:protein targeting to lysosome; IEA:Ensembl. DR GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl. DR GO; GO:0043471; P:regulation of cellular carbohydrate catabolic process; IEA:Ensembl. DR GO; GO:1905123; P:regulation of glucosylceramidase activity; IEA:Ensembl. DR GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl. DR InterPro; IPR002159; CD36_fam. DR InterPro; IPR005429; LimpII. DR PANTHER; PTHR11923; PTHR11923; 1. DR Pfam; PF01130; CD36; 1. DR PRINTS; PR01609; CD36FAMILY. DR PRINTS; PR01611; LIMPII. PE 3: Inferred from homology; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000240080}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1..26 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 27..478 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5015317155" FT TRANSMEM 438..458 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 478 AA; 54295 MW; C03A145C68F31298 CRC64; MGRCCFYTAG TLSLLLLVTS VTLLVARVFQ KAVDQSIEKK IVLRNGTEAF DSWEKPPLPV YTQFYFFNVT NPEEILRGET PRVEEVGPYT YRELRNKANI QFGDNGTTIS AVSNKAYVFE RDQSVGDPKI DLIRTLNIPV LTVIEWSQVR FLREIIEAML KAYQQKLFVT HTVDELLWGY KDEILSLIHV FRPDISPYFG LFYEKNGTND GDYVFLTGED SYLNFTKIVE WNGKTSLDWW ITDKCNMING TDGDSFHPLI TKDEVLYVFP SDFCRSVYIT FSDYESVQGL PAFRYKVPAE ILANTSDNAG FCIPEGNCLG SGVLNVSICK NGAPIIMSFP HFYQADERFV SAVEGMHPNK EDHETFVDIN PLTGIILKAA KRFQINIYVK KLDDFVETGD IRTMVFPVMY LNESVHIDKE TASRLKSMIN TTLIITNIPY IIMALGVFFG LVFTWLACKG QGSMDEGTAD ERAPLIRT //