ID A0A2R8Y8C1_HUMAN Unreviewed; 1669 AA. AC A0A2R8Y8C1; DT 20-JUN-2018, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 1. DT 20-JUN-2018, entry version 1. DE SubName: Full=Chromodomain-helicase-DNA-binding protein 4 {ECO:0000313|Ensembl:ENSP00000496707}; DE Flags: Fragment; GN Name=CHD4 {ECO:0000313|Ensembl:ENSP00000496707}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000496707, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000496707, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16541075; DOI=10.1038/nature04569; RG Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team; RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., RA Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., RA Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., RA Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., RA Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., RA Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., RA Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., RA Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., RA Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., RA Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., RA Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., RA Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., RA Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., RA Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., RA Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., RA Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., RA Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., RA Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., RA Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., RA Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., RA Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., RA Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., RA Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., RA Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., RA Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., RA Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., RA Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., RA Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., RA Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., RA Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., RA Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., RA Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., RA Kucherlapati R., Weinstock G., Gibbs R.A., null.; RT "The finished DNA sequence of human chromosome 12."; RL Nature 440:346-351(2006). RN [2] {ECO:0000313|Ensembl:ENSP00000496707} RP IDENTIFICATION. RG Ensembl; RL Submitted (APR-2018) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC006064; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENST00000644289; ENSP00000496707; ENSG00000111642. DR HGNC; HGNC:1919; CHD4. DR OpenTargets; ENSG00000111642; -. DR GeneTree; ENSGT00760000119067; -. DR Proteomes; UP000005640; Chromosome 12. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSP00000496707}. FT NON_TER 1669 1669 {ECO:0000313|Ensembl:ENSP00000496707}. SQ SEQUENCE 1669 AA; 189386 MW; 1559BE9F943A5BB1 CRC64; LGSPSPCSAG SEEEDMDALL NNSLPPPHPE NEEDPEEDLS ETETPKLKKK KKPKKPRDPK IPKSKRQKKE LGDSSGEGPE FVEEEEEVAL RSDSEGSDYT PGKKKKKKLG PKKEKKSKSK RKEEEEEEDD DDDSKEPKSS AQLLEDWGME DIDHVFSEED YRTLTNYKAF SQFVRPLIAA KNPKIAVSKM MMVLGAKWRE FSTNNPFKGS SGASVAAAAA AAVAVVESMV TATEVAPPPP PVEVPIRKAK TKEGKGPNAR RKPKGSPRVP DAKKPKPKKV APLKIKLGGF GSKRKRSSSE DDDLDVESDF DDASINSYSV SDGSTSRSSR SRKKLRTTKK KKKGEEEVTA VDGYETDHQD YCEVCQQGGE IILCDTCPRA YHMVCLDPDM EKAPEGKWSC PHCEKEGIQW EAKEDNSEGE EILEEVGGDL EEEDDHHMEF CRVCKDGGEL LCCDTCPSSY HIHCLNPPLP EIPNGEWLCP RCTCPALKGK VQKILIWKWG QPPSPTPVPR PPDADPNTPS PKPLEGRPER QFFVKWQGMS YWHCSWVSEL QLELHCQVMF RNYQRKNDMD EPPSGDFGGD EEKSRKRKNK DPKFAEMEER FYRYGIKPEW MMIHRILNHS VDKKGHVHYL IKWRDLPYDQ ASWESEDVEI QDYDLFKQSY WNHRELMRGE EGRPGKKLKK VKLRKLERPP ETPTVDPTVK YERQPEYLDA TGGTLHPYQM EGLNWLRFSW AQGTDTILAD EMGLGKTVQT AVFLYSLYKE GHSKGPFLVS APLSTIINWE REFEMWAPDM YVVTYVGDKD SRAIIRENEF SFEDNAIRGG KKASRMKKEA SVKFHVLLTS YELITIDMAI LGSIDWACLI VDEAHRLKNN QSKFFRVLNG YSLQHKLLLT GTPLQNNLEE LFHLLNFLTP ERFHNLEGFL EEFADIAKED QIKKLHDMLG PHMLRRLKAD VFKNMPSKTE LIVRVELSPM QKKYYKYILT RNFEALNARG GGNQVSLLNV VMDLKKCCNH PYLFPVAAME APKMPNGMYD GSALIRASGK LLLLQKMLKN LKEGGHRVLI FSQMTKMLDL LEDFLEHEGY KYERIDGGIT GNMRQEAIDR FNAPGAQQFC FLLSTRAGGL GINLATADTV IIYDSDWNPH NDIQAFSRAH RIGQNKKVMI YRFVTRASVE ERITQVAKKK MMLTHLVVRP GLGSKTGSMS KQELDDILKF GTEELFKDEA TDGGGDNKEG EDSSVIHYDD KAIERLLDRN QDETEDTELQ GMNEYLSSFK VAQYVVREEE MGEEEEVERE IIKQEESVDP DYWEKLLRHH YEQQQEDLAR NLGKGKRIRK QVNYNDGSQE DRGVCGRPRP PPMGRSTRAV GPAHLPSLPP DWQDDQSDNQ SDYSVASEEG DEDFDERSEA PRRPSRKGLR NDKDKPLPPL LARVGGNIEV LGFNARQRKA FLNAIMRYGM PPQDAFTTQW LVRDLRGKSE KEFKAYVSLF MRHLCEPGAD GAETFADGVP REGLSRQHVL TRIGVMSLIR KKVQEFEHVN GRWSMPELAE VEENKKMSQP GSPSPKTPTP STPGDTQPNT PAPVPPAEDG IKIEENSLKE EESIEGEKEV KSTAPETAIE CTQAPAPASE DEKVVVEPPE GEEKVEKAEV KERTEEPMET EPKGAADVEK VEEKSAIDL //