ID A0A2P7YK09_9ASCO Unreviewed; 613 AA. AC A0A2P7YK09; DT 23-MAY-2018, integrated into UniProtKB/TrEMBL. DT 23-MAY-2018, sequence version 1. DT 07-OCT-2020, entry version 11. DE RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}; DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}; GN ORFNames=C7M61_004116 {ECO:0000313|EMBL:PSK36292.1}; OS [Candida] pseudohaemulonis. OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Metschnikowiaceae; Clavispora; Clavispora/Candida clade. OX NCBI_TaxID=418784 {ECO:0000313|EMBL:PSK36292.1, ECO:0000313|Proteomes:UP000241107}; RN [1] {ECO:0000313|EMBL:PSK36292.1, ECO:0000313|Proteomes:UP000241107} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=B12108 {ECO:0000313|EMBL:PSK36292.1, RC ECO:0000313|Proteomes:UP000241107}; RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N., RA Cuomo C.A.; RT "Candida pseudohaemulonii genome assembly and annotation."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; CC Evidence={ECO:0000256|ARBA:ARBA00001433}; CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775}; CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PSK36292.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; PYFQ01000012; PSK36292.1; -; Genomic_DNA. DR Proteomes; UP000241107; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. DR CDD; cd14334; UBA_SNF1_fungi; 1. DR InterPro; IPR032270; AMPK_C. DR InterPro; IPR028375; KA1/Ssp2_C. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR InterPro; IPR013896; SNF1_UBA. DR Pfam; PF16579; AdenylateSensor; 1. DR Pfam; PF00069; Pkinase; 1. DR Pfam; PF08587; UBA_2; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF103243; SSF103243; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW Kinase {ECO:0000313|EMBL:PSK36292.1}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}; KW Reference proteome {ECO:0000313|Proteomes:UP000241107}; KW Transferase {ECO:0000313|EMBL:PSK36292.1}. FT DOMAIN 51..302 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT REGION 1..45 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 389..413 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 9..24 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 28..45 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 390..409 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 613 AA; 69549 MW; 80CDE3126589B7A8 CRC64; MSEEGKLSGH HRHHHHHSHH GHHGHDLKQQ QQQQFPPQGT APSSANRIGK YQIIKTLGEG SFGKVKLAEH STTGQRVALK IINRKTLAKS DMQGRVEREI SYLRLLRHPH IIKLYDVIKS KDEIIMVIEY AGKELFDYIV QRGRMPEDEA RRFFQQIIAA VEYCHRHKIV HRDLKPENLL LDDHLNVKIA DFGLSNIMTD GNFLKTSCGS PNYAAPEVIS GKLYAGPEVD VWSSGVILYV MLCGRLPFDD EFIPALFKKI SNGVYTLPNY LSEGAKKILT KMLVVNPLNR VTIHEIMEDP WFKEGIEDYL LPPDLSKTIH NKIDIDEDVI NALSVTMGYD RDEILNTINS CNKQQYPQQQ QNEILDAYLL MKENHSLVKD LKKNKTEHMD NFLSSSPPPS WSSPQGEEAT ATHRAPGVLQ SLTYQTLATV PDLSTLPNST IAILPSSLPS IHRASMMNVS EQGSSKINPV SSKKLKTKWH FGIRSRSYPL DVMGEIYRAL KNLGAEWAKP TEEELWTIRV RWKYGPCLVD ETVKEGESVP PALMKMQIQL FQLEPNNYLV DFKFDGWEST TTQDGKPAGK QDVDEMSSFS AYPFLHLATR LIMELAVNST QAQ //