ID   A0A2P6MIA2_ALKUR        Unreviewed;       270 AA.
AC   A0A2P6MIA2;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   02-APR-2025, entry version 22.
DE   SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:PRO66012.1};
GN   ORFNames=C6I21_06840 {ECO:0000313|EMBL:PRO66012.1};
OS   Alkalicoccus urumqiensis (Bacillus urumqiensis).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC   Alkalicoccus.
OX   NCBI_TaxID=1548213 {ECO:0000313|EMBL:PRO66012.1, ECO:0000313|Proteomes:UP000243650};
RN   [1] {ECO:0000313|EMBL:PRO66012.1, ECO:0000313|Proteomes:UP000243650}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BZ-SZ-XJ18 {ECO:0000313|EMBL:PRO66012.1,
RC   ECO:0000313|Proteomes:UP000243650};
RA   Zhao B., Liao Z.;
RT   "Bacillus urumqiensis sp. nov., a moderately haloalkaliphilic bacterium
RT   isolated from a salt lake.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRO66012.1}.
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DR   EMBL; PVNS01000005; PRO66012.1; -; Genomic_DNA.
DR   RefSeq; WP_105958696.1; NZ_PVNS01000005.1.
DR   AlphaFoldDB; A0A2P6MIA2; -.
DR   Proteomes; UP000243650; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR048647; RlmA_N.
DR   InterPro; IPR016718; rRNA_m1G-MeTrfase_A_prd.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   Pfam; PF21302; Zn_ribbon_RlmA; 1.
DR   PIRSF; PIRSF018249; MyrA_prd; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR018249-1};
KW   Methyltransferase {ECO:0000313|EMBL:PRO66012.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243650};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRSR:PIRSR018249-2};
KW   Transferase {ECO:0000313|EMBL:PRO66012.1};
KW   Zinc {ECO:0000256|PIRSR:PIRSR018249-1}.
FT   DOMAIN          19..54
FT                   /note="23S rRNA (guanine(745)-N(1))-methyltransferase N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21302"
FT   DOMAIN          96..178
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   BINDING         21
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT   BINDING         24
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT   BINDING         37
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT   BINDING         41
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT   BINDING         79
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT   BINDING         103..104
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT   BINDING         189
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
SQ   SEQUENCE   270 AA;  29963 MW;  74A49AC3DC4A715F CRC64;
     MMSKREKRRL RIDELFPLFR CPHCRQELYV SDNDLRCRTG HTFPIAKQGH VHLLNGKGAD
     DYSKELFQAR KDVLQEGIYD PLYENLTPLL PEGGTVLDAG CGEGSHLTAL GKKKTFDGIG
     IDNAKAAVQM AAAQSDDMVF AAGDLADAPM VSGRLDGILN VLSPANYTEF KRMLKPEGRV
     IKVIPNTSYL TELRTAAGKA PYSNEEVRRG FFDAFPHAEE IHTSWNAPLT PASAALLWKM
     TPLTWNTAMP ETFQPETVTI DITILHAFTN
//