ID A0A2P4W2E0_CAERE Unreviewed; 428 AA. AC A0A2P4W2E0; DT 23-MAY-2018, integrated into UniProtKB/TrEMBL. DT 23-MAY-2018, sequence version 1. DT 28-JUN-2023, entry version 19. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:POM43719.1}; GN ORFNames=FL81_05944 {ECO:0000313|EMBL:POM43719.1}; OS Caenorhabditis remanei (Caenorhabditis vulgaris). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=31234 {ECO:0000313|EMBL:POM43719.1}; RN [1] {ECO:0000313|EMBL:POM43719.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PX356 {ECO:0000313|EMBL:POM43719.1}; RX PubMed=26114425; DOI=10.1371/journal.pgen.1005323; RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M., RA Ahearne T.E., Cutter A.D., Phillips P.C.; RT "Reproductive Mode and the Evolution of Genome Size and Structure in RT Caenorhabditis Nematodes."; RL PLoS Genet. 11:e1005323-e1005323(2015). RN [2] {ECO:0000313|EMBL:POM43719.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PX356 {ECO:0000313|EMBL:POM43719.1}; RX PubMed=26394399; DOI=10.1371/journal.pgen.1005497; RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M., RA Ahearne T.E., Cutter A.D., Phillips P.C.; RT "Correction: Reproductive Mode and the Evolution of Genome Size and RT Structure in Caenorhabditis Nematodes."; RL PLoS Genet. 11:e1005497-e1005497(2015). RN [3] {ECO:0000313|EMBL:POM43719.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=PX356 {ECO:0000313|EMBL:POM43719.1}; RA Banno H., Chua N.-H.; RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PROSITE-ProRule:PRU00407, ECO:0000256|RuleBase:RU004334}. CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. CC {ECO:0000256|RuleBase:RU004334}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:POM43719.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LFJK02000008; POM43719.1; -; Genomic_DNA. DR AlphaFoldDB; A0A2P4W2E0; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR CDD; cd06916; NR_DBD_like; 1. DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1. DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1. DR InterPro; IPR035500; NHR-like_dom_sf. DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd. DR InterPro; IPR001723; Nuclear_hrmn_rcpt. DR InterPro; IPR001628; Znf_hrmn_rcpt. DR InterPro; IPR013088; Znf_NHR/GATA. DR PANTHER; PTHR47519; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-31-RELATED; 1. DR PANTHER; PTHR47519:SF2; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-97; 1. DR Pfam; PF00104; Hormone_recep; 1. DR Pfam; PF00105; zf-C4; 1. DR PRINTS; PR00398; STRDHORMONER. DR PRINTS; PR00047; STROIDFINGER. DR SMART; SM00430; HOLI; 1. DR SMART; SM00399; ZnF_C4; 1. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1. DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1. DR PROSITE; PS51843; NR_LBD; 1. DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1. DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1. PE 3: Inferred from homology; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU00407}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|RuleBase:RU004334}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE- KW ProRule:PRU00407}; KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334}; KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|PROSITE- KW ProRule:PRU00407}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, KW ECO:0000256|PROSITE-ProRule:PRU00407}; KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00407}. FT DOMAIN 3..79 FT /note="Nuclear receptor" FT /evidence="ECO:0000259|PROSITE:PS51030" FT DOMAIN 160..396 FT /note="NR LBD" FT /evidence="ECO:0000259|PROSITE:PS51843" FT DNA_BIND 3..79 FT /note="Nuclear receptor" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00407" FT REGION 101..125 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 428 AA; 48408 MW; D1622354C12A360B CRC64; MFSDTCVVCG DRACSHLYYG VAACHGCKCF FWRTVKSKLN YTCRYGGNCS ISTAGRNACR YCRFHQCLSV GMKMEGWSFD TFNDKKQKKF TAVKMDRKLT KRKREKTDGD DTDDGGNQES YDNKIDAKRA KSDNRLLVSS LLLIDKTSSD GNAKLSSLHF VQPSLQNLLE EPELLDGFRS EMSYRATRQA DDQLCYDNER RLVTWAIDWC RQTAEIGDVH HTNDKIALLR ACCGPLVLLE LGCQSSSFSQ SDAQIPLCNN SFLPAHIIPP SASFLNWKTI QSLSKWTQRE LKPLCLQAKE IGLLKALIVL NPEAHGLSQD AESSIRMLRE RVHTALFQQL MENSEPFAAA SRLAQIMLLI PQLALMGVEV IEQVRVRNTF NKYSAFGEGL LFWQLYGDIF DDQHNDDNYL EHSASCSPTD SQYTNDSS //