ID A0A2P4VTN9_CAERE Unreviewed; 836 AA. AC A0A2P4VTN9; DT 23-MAY-2018, integrated into UniProtKB/TrEMBL. DT 23-MAY-2018, sequence version 1. DT 29-MAY-2024, entry version 14. DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156}; GN ORFNames=FL81_13375 {ECO:0000313|EMBL:POM40657.1}; OS Caenorhabditis remanei (Caenorhabditis vulgaris). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=31234 {ECO:0000313|EMBL:POM40657.1}; RN [1] {ECO:0000313|EMBL:POM40657.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PX356 {ECO:0000313|EMBL:POM40657.1}; RX PubMed=26114425; DOI=10.1371/journal.pgen.1005323; RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M., RA Ahearne T.E., Cutter A.D., Phillips P.C.; RT "Reproductive Mode and the Evolution of Genome Size and Structure in RT Caenorhabditis Nematodes."; RL PLoS Genet. 11:e1005323-e1005323(2015). RN [2] {ECO:0000313|EMBL:POM40657.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PX356 {ECO:0000313|EMBL:POM40657.1}; RX PubMed=26394399; DOI=10.1371/journal.pgen.1005497; RA Fierst J.L., Willis J.H., Thomas C.G., Wang W., Reynolds R.M., RA Ahearne T.E., Cutter A.D., Phillips P.C.; RT "Correction: Reproductive Mode and the Evolution of Genome Size and RT Structure in Caenorhabditis Nematodes."; RL PLoS Genet. 11:e1005497-e1005497(2015). RN [3] {ECO:0000313|EMBL:POM40657.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=PX356 {ECO:0000313|EMBL:POM40657.1}; RA Banno H., Chua N.-H.; RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the patched family. CC {ECO:0000256|ARBA:ARBA00005585}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:POM40657.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LFJK02000063; POM40657.1; -; Genomic_DNA. DR AlphaFoldDB; A0A2P4VTN9; -. DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:TreeGrafter. DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter. DR GO; GO:0006897; P:endocytosis; IEA:TreeGrafter. DR GO; GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IEA:EnsemblMetazoa. DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2. DR InterPro; IPR003392; Ptc/Disp. DR InterPro; IPR000731; SSD. DR PANTHER; PTHR10796; PATCHED-RELATED; 1. DR PANTHER; PTHR10796:SF96; PATCHED-RELATED PROTEIN 9; 1. DR Pfam; PF02460; Patched; 1. DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2. DR PROSITE; PS50156; SSD; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 264..283 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 295..315 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 321..344 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 383..407 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 469..487 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 660..682 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 689..709 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 715..741 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 762..780 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 786..806 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 273..413 FT /note="SSD" FT /evidence="ECO:0000259|PROSITE:PS50156" SQ SEQUENCE 836 AA; 95176 MW; 70F4827F2130486C CRC64; MKSLNFQSVV SQFFEYESTV VVRWPLPFII IPPLLTVSIV TLTVTNFHLN VTNDTLQVFL PDDMRSLRDL KELLDLFPPK DAQRDTYSIF GSKFVYTVIE DENPEGNILS SSGIQRMARL HKFVMGLETR QGDNVAMNCL RNRDDEACTM HPIAFALEDS TPEFAIQFLL RYPNLKFGDF VVDNAMVFGG VKIEPKTHDK EGNSPIQSSK AVRMTYIFEA SESTERWIDL FLTAIPRYKE SNSTILWSSS KSLAKEMERN GELLIPWMPW TSLVLVVFCM FACSSFQVVK SQPFIGFFAM FNATMATIAS TSLLIYLQYP FLPLVFIMPF LVVSIGTDNM FLMLKSWRMT KKSSNEEQRY IYALTESAAS LFLTSLTDGL SFAIGRVFCT YCAMAILFMF IFQVTFFNAV MSLCCRREVS GRHPVFCCYD TAPSNETKIM KQHSDPSFDF ASIVAKYLFK ILNPWPSRIG VFCIFIVYLF TAIHYAIGLP LGLDLKLLAP DDSYVSKELE AQERLFADYG GFCFALVRAE NISIRDPIVR RDLMRLYHDL GGSEYSSPAE FWLQPFEKSR RGKKYSESEF SDELHTFLAK EPHLKFRNDI RFTMTGKIEA IKMMFRVRRL GKDNDAPRAE YMRRIMETSG FSGFVYDTSF LLVDQQMTTV YNVIIDVVSA ILTMLSICVL MVPRPVSAMC IAFAILSVNI GVIGALAATN TRLDIISMIT IVMSVGFSVD YVTHTTFHFV IQRDNRLEKC LLVMTEPILQ SALSTAIGVS LLSFVHSYIV RTFVNTVFFV VGLGILHGLI FLPVLLDTIV PDSEYMVAYE PHQDEEESHY EDPYGL //