ID A0A2P1VJR9_9BURK Unreviewed; 401 AA. AC A0A2P1VJR9; DT 23-MAY-2018, integrated into UniProtKB/TrEMBL. DT 23-MAY-2018, sequence version 1. DT 29-SEP-2021, entry version 13. DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AVQ85420.1}; GN ORFNames=C4F17_30855 {ECO:0000313|EMBL:AVQ85420.1}; OS Variovorax sp. PMC12. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Comamonadaceae; Variovorax. OX NCBI_TaxID=2126319 {ECO:0000313|EMBL:AVQ85420.1, ECO:0000313|Proteomes:UP000240852}; RN [1] {ECO:0000313|EMBL:AVQ85420.1, ECO:0000313|Proteomes:UP000240852} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PMC12 {ECO:0000313|EMBL:AVQ85420.1, RC ECO:0000313|Proteomes:UP000240852}; RA Weon H.-Y., Lee S.A.; RT "Whole-genome sequence of Variovorax boronicumulans PMC12."; RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family. CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP027774; AVQ85420.1; -; Genomic_DNA. DR EnsemblBacteria; AVQ85420; AVQ85420; C4F17_30855. DR KEGG; vam:C4F17_30855; -. DR Proteomes; UP000240852; Chromosome 2. DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro. DR CDD; cd00751; thiolase; 1. DR Gene3D; 3.40.47.10; -; 2. DR InterPro; IPR002155; Thiolase. DR InterPro; IPR016039; Thiolase-like. DR InterPro; IPR020610; Thiolase_AS. DR InterPro; IPR020617; Thiolase_C. DR InterPro; IPR020613; Thiolase_CS. DR InterPro; IPR020616; Thiolase_N. DR Pfam; PF02803; Thiolase_C; 1. DR Pfam; PF00108; Thiolase_N; 1. DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1. DR SUPFAM; SSF53901; SSF53901; 2. DR TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1. DR PROSITE; PS00737; THIOLASE_2; 1. DR PROSITE; PS00099; THIOLASE_3; 1. PE 3: Inferred from homology; KW Acyltransferase {ECO:0000256|RuleBase:RU003557}; KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AVQ85420.1}. FT DOMAIN 5..228 FT /note="Thiolase_N" FT /evidence="ECO:0000259|Pfam:PF00108" FT DOMAIN 280..400 FT /note="Thiolase_C" FT /evidence="ECO:0000259|Pfam:PF02803" FT ACT_SITE 91 FT /note="Acyl-thioester intermediate" FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1" FT ACT_SITE 357 FT /note="Proton acceptor" FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1" FT ACT_SITE 387 FT /note="Proton acceptor" FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1" SQ SEQUENCE 401 AA; 42619 MW; C6DB76BE132E8602 CRC64; MQEAMIFDAL RTPRGKGKAD GSLYEVNPVA LLGGLMRALQ RRNDLDTAQI EDTLIGCVQP YGEQSMCIGK TAALYAGWDW RVPGVQLDRY CGSGLEAVNI AAQKVRSGWE DLVVAGGVES MSRIAMGGAP NARDTYPPLN FRLQPVPQGI GADLIATLDG HSRDDVDAFA AASQRKAANA RSQGWFDRSV VPVTDANGLA VLAQDEYIRP DTTADSLGRL KPAFAQQGEF GFDAIAQFKY PQVDRIRHVH TAGNSSGIVD GASLMLIGTE AKGRELGLVP RARVLSVGVV GAEPTIMLAG PAPASRIALR KAGLTVDDID LFEVNEAFAS VVLRFMSDMQ VPPEKVNVNG GAIALGHPLG ATGCMLLGTL LDELERRQLK RGLVTLCVAG GMGIATIIER L //