ID A0A2N1GGK4_9GAMM Unreviewed; 259 AA. AC A0A2N1GGK4; DT 25-APR-2018, integrated into UniProtKB/TrEMBL. DT 25-APR-2018, sequence version 1. DT 05-DEC-2018, entry version 4. DE RecName: Full=5'-nucleotidase SurE {ECO:0000256|HAMAP-Rule:MF_00060}; DE EC=3.1.3.5 {ECO:0000256|HAMAP-Rule:MF_00060}; DE AltName: Full=Nucleoside 5'-monophosphate phosphohydrolase {ECO:0000256|HAMAP-Rule:MF_00060}; GN Name=surE {ECO:0000256|HAMAP-Rule:MF_00060}; GN ORFNames=CXF96_12850 {ECO:0000313|EMBL:PKH73266.1}; OS Stenotrophomonas sp. Betaine-02u-21. OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; OC Xanthomonadaceae; Stenotrophomonas. OX NCBI_TaxID=2058301 {ECO:0000313|EMBL:PKH73266.1, ECO:0000313|Proteomes:UP000233835}; RN [1] {ECO:0000313|EMBL:PKH73266.1, ECO:0000313|Proteomes:UP000233835} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Betaine-02u-21 {ECO:0000313|EMBL:PKH73266.1, RC ECO:0000313|Proteomes:UP000233835}; RA Collins E., Ducluzeau A.-L.; RT "Pharmacopeia of the Arctic Ocean."; RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Nucleotidase that shows phosphatase activity on CC nucleoside 5'-monophosphates. {ECO:0000256|HAMAP-Rule:MF_00060}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + CC phosphate; Xref=Rhea:RHEA:12484, ChEBI:CHEBI:15377, CC ChEBI:CHEBI:18254, ChEBI:CHEBI:43474, ChEBI:CHEBI:58043; CC EC=3.1.3.5; Evidence={ECO:0000256|HAMAP-Rule:MF_00060, CC ECO:0000256|SAAS:SAAS00978885}; CC -!- COFACTOR: CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; CC Evidence={ECO:0000256|HAMAP-Rule:MF_00060}; CC Note=Binds 1 divalent metal cation per subunit. CC {ECO:0000256|HAMAP-Rule:MF_00060}; CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00060, CC ECO:0000256|SAAS:SAAS00978873}. CC -!- SIMILARITY: Belongs to the SurE nucleotidase family. CC {ECO:0000256|HAMAP-Rule:MF_00060, ECO:0000256|SAAS:SAAS00978879}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:PKH73266.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; PJAW01000125; PKH73266.1; -; Genomic_DNA. DR RefSeq; WP_042613041.1; NZ_PJAW01000125.1. DR Proteomes; UP000233835; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0008253; F:5'-nucleotidase activity; IEA:UniProtKB-UniRule. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. DR Gene3D; 3.40.1210.10; -; 1. DR HAMAP; MF_00060; SurE; 1. DR InterPro; IPR030048; SurE. DR InterPro; IPR002828; SurE-like_Pase/nucleotidase. DR InterPro; IPR036523; SurE-like_sf. DR Pfam; PF01975; SurE; 1. DR TIGRFAMs; TIGR00087; surE; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000233835}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00060, KW ECO:0000256|SAAS:SAAS00978882}; KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_00060, KW ECO:0000256|SAAS:SAAS00978867}; KW Metal-binding {ECO:0000256|HAMAP-Rule:MF_00060, KW ECO:0000256|SAAS:SAAS00978876}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00060, KW ECO:0000256|SAAS:SAAS00978865}. FT DOMAIN 3 185 SurE. {ECO:0000259|Pfam:PF01975}. FT METAL 8 8 Divalent metal cation. FT {ECO:0000256|HAMAP-Rule:MF_00060}. FT METAL 9 9 Divalent metal cation. FT {ECO:0000256|HAMAP-Rule:MF_00060}. FT METAL 40 40 Divalent metal cation. FT {ECO:0000256|HAMAP-Rule:MF_00060}. FT METAL 92 92 Divalent metal cation. FT {ECO:0000256|HAMAP-Rule:MF_00060}. SQ SEQUENCE 259 AA; 27423 MW; 5FF2317A189F6663 CRC64; MRVLVSNDDG VDAPGIAMLA AVLRQAGHEV TVVAPDRDRS GASNSLTLDL PIRLKRLDHH TVSVAGTPTD CVHLALTGLL DQEPDIVVSG INNVANLGDD VIYSGTVSAA MEGRHLGLPA VAMSLVSHNH EPKHFQTAAR AAVEIVAQLK ADPLPADTIL NVNVPDLPWS EVKGFEVTRL GNRHRAEGCI AQKDPRGNAV YWIGPAGREQ DSGPGTDFHA VRTGFISITP IQVDLTRYQA LEKVASWVGG LSAALGRPA //