ID A0A2L1KVR6_9HIV1 Unreviewed; 101 AA. AC A0A2L1KVR6; DT 25-APR-2018, integrated into UniProtKB/TrEMBL. DT 25-APR-2018, sequence version 1. DT 12-SEP-2018, entry version 5. DE RecName: Full=Protein Tat {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00396010}; GN Name=tat {ECO:0000313|EMBL:AVE26626.1}; OS Human immunodeficiency virus 1. OC Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:AVE26626.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:AVE26626.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=13612_1_11.3 {ECO:0000313|EMBL:AVE26626.1}; RX PubMed=29389981; RG ICONIC Consortium; RA Yebra G., Frampton D., Gallo Cassarino T., Raffle J., Hubb J., RA Ferns R.B., Waters L., Tong C.Y.W., Kozlakidis Z., Hayward A., RA Kellam P., Pillay D., Clark D., Nastouli E., Leigh Brown A.J.; RT "A high HIV-1 strain variability in London, UK, revealed by full- RT genome analysis: Results from the ICONIC project."; RL PLoS ONE 13:e0192081-e0192081(2018). CC -!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus CC {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581732}. CC -!- SIMILARITY: Belongs to the lentiviruses Tat family. CC {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581731}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MF109395; AVE26626.1; -; Genomic_RNA. DR GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0001070; F:RNA-binding transcription regulator activity; IEA:InterPro. DR GO; GO:0050434; P:positive regulation of viral transcription; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR GO; GO:0016032; P:viral process; IEA:UniProtKB-KW. DR Gene3D; 4.10.20.10; -; 1. DR HAMAP; MF_04079; HIV_TAT; 1. DR InterPro; IPR001831; IV_Tat. DR InterPro; IPR036963; Tat_dom_sf. DR Pfam; PF00539; Tat; 1. DR PRINTS; PR00055; HIVTATDOMAIN. PE 3: Inferred from homology; KW Activator {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111091}; KW Host nucleus {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00473431}; KW Host-virus interaction {ECO:0000256|SAAS:SAAS00111166}; KW RNA-binding {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111359}; KW Transcription {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111391}; KW Transcription regulation {ECO:0000256|RuleBase:RU003311, KW ECO:0000256|SAAS:SAAS00111074}. SQ SEQUENCE 101 AA; 11604 MW; F24AB13FBE7AE8BB CRC64; MEPVDPRLEP WKHPGSQPKT DCTKCYCKKC CFHCQVCFMK KGLGISYGRK KRRQRRKTPN DGQIHQIPLS KQPTSQPSGD PTGPQKSEKK VERKTETDPV H //