ID A0A2K6NYT4_RHIRO Unreviewed; 108 AA. AC A0A2K6NYT4; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 29-MAY-2024, entry version 30. DE SubName: Full=Ring-box 1 {ECO:0000313|Ensembl:ENSRROP00000009431.1}; GN Name=RBX1 {ECO:0000313|Ensembl:ENSRROP00000009431.1}; OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Colobinae; Rhinopithecus. OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000009431.1, ECO:0000313|Proteomes:UP000233200}; RN [1] {ECO:0000313|Ensembl:ENSRROP00000009431.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2023) to UniProtKB. CC -!- PATHWAY: Protein modification; protein ubiquitination. CC {ECO:0000256|ARBA:ARBA00004906}. CC -!- SIMILARITY: Belongs to the RING-box family. CC {ECO:0000256|ARBA:ARBA00009273}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_010375845.1; XM_010377543.1. DR AlphaFoldDB; A0A2K6NYT4; -. DR SMR; A0A2K6NYT4; -. DR STRING; 61622.ENSRROP00000009431; -. DR Ensembl; ENSRROT00000033520.1; ENSRROP00000009431.1; ENSRROG00000029154.1. DR GeneID; 104673455; -. DR KEGG; rro:104673455; -. DR CTD; 9978; -. DR GeneTree; ENSGT00940000155618; -. DR OMA; NACPLDN; -. DR OrthoDB; 3546417at2759; -. DR Proteomes; UP000233200; Unplaced. DR GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0031464; C:Cul4A-RING E3 ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0031465; C:Cul4B-RING E3 ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0031466; C:Cul5-RING ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0031467; C:Cul7-RING ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl. DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IEA:Ensembl. DR GO; GO:0097602; F:cullin family protein binding; IEA:Ensembl. DR GO; GO:0061663; F:NEDD8 ligase activity; IEA:Ensembl. DR GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:Ensembl. DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl. DR GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:Ensembl. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl. DR GO; GO:1902883; P:negative regulation of response to oxidative stress; IEA:Ensembl. DR GO; GO:0032480; P:negative regulation of type I interferon production; IEA:Ensembl. DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:Ensembl. DR GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl. DR GO; GO:1902499; P:positive regulation of protein autoubiquitination; IEA:Ensembl. DR GO; GO:1904263; P:positive regulation of TORC1 signaling; IEA:Ensembl. DR GO; GO:0070936; P:protein K48-linked ubiquitination; IEA:Ensembl. DR GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl. DR GO; GO:0045116; P:protein neddylation; IEA:Ensembl. DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl. DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl. DR GO; GO:0042110; P:T cell activation; IEA:Ensembl. DR GO; GO:0140627; P:ubiquitin-dependent protein catabolic process via the C-end degron rule pathway; IEA:Ensembl. DR CDD; cd16485; mRING-H2-C3H2C2D_RBX1; 1. DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR024766; Znf_RING_H2. DR PANTHER; PTHR11210:SF2; E3 UBIQUITIN-PROTEIN LIGASE RBX1; 1. DR PANTHER; PTHR11210; RING BOX; 1. DR Pfam; PF12678; zf-rbx1; 1. DR SUPFAM; SSF57850; RING/U-box; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 3: Inferred from homology; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Reference proteome {ECO:0000313|Proteomes:UP000233200}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00175}. FT DOMAIN 53..98 FT /note="RING-type" FT /evidence="ECO:0000259|PROSITE:PS50089" SQ SEQUENCE 108 AA; 12274 MW; 30FC5ADF66096C0E CRC64; MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM DLCIECQANQ ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE WEFQKYGH //