ID A0A2K6M1R1_RHIBE Unreviewed; 381 AA. AC A0A2K6M1R1; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 23-MAY-2018, entry version 3. DE SubName: Full=Cysteine rich angiogenic inducer 61 {ECO:0000313|Ensembl:ENSRBIP00000029718}; GN Name=CYR61 {ECO:0000313|Ensembl:ENSRBIP00000029718}; OS Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus. OX NCBI_TaxID=61621 {ECO:0000313|Ensembl:ENSRBIP00000029718, ECO:0000313|Proteomes:UP000233180}; RN [1] {ECO:0000313|Ensembl:ENSRBIP00000029718, ECO:0000313|Proteomes:UP000233180} RP NUCLEOTIDE SEQUENCE. RA Wu, C.-I. and Zhang, Y.; RT "Genome of Rhinopithecus bieti."; RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSRBIP00000029718} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2018) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00567783}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_017706627.1; XM_017851138.1. DR Ensembl; ENSRBIT00000053672; ENSRBIP00000029718; ENSRBIG00000038743. DR GeneID; 108514716; -. DR GeneTree; ENSGT00760000119225; -. DR Proteomes; UP000233180; Unplaced. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro. DR GO; GO:0001558; P:regulation of cell growth; IEA:InterPro. DR Gene3D; 2.20.100.10; -; 1. DR InterPro; IPR006207; Cys_knot_C. DR InterPro; IPR006208; Glyco_hormone_CN. DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf. DR InterPro; IPR000867; IGFBP-like. DR InterPro; IPR012395; IGFBP_CNN. DR InterPro; IPR017891; Insulin_GF-bd_Cys-rich_CS. DR InterPro; IPR000884; TSP1_rpt. DR InterPro; IPR036383; TSP1_rpt_sf. DR InterPro; IPR001007; VWF_dom. DR Pfam; PF00007; Cys_knot; 1. DR Pfam; PF00219; IGFBP; 1. DR Pfam; PF00093; VWC; 1. DR PIRSF; PIRSF036495; IGFBP_rP_CNN; 1. DR SMART; SM00041; CT; 1. DR SMART; SM00121; IB; 1. DR SMART; SM00209; TSP1; 1. DR SMART; SM00214; VWC; 1. DR SUPFAM; SSF57184; SSF57184; 1. DR SUPFAM; SSF82895; SSF82895; 1. DR PROSITE; PS01185; CTCK_1; 1. DR PROSITE; PS01225; CTCK_2; 1. DR PROSITE; PS00222; IGFBP_N_1; 1. DR PROSITE; PS51323; IGFBP_N_2; 1. DR PROSITE; PS50092; TSP1; 1. DR PROSITE; PS01208; VWFC_1; 1. DR PROSITE; PS50184; VWFC_2; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000233180}; KW Disulfide bond {ECO:0000256|SAAS:SAAS00509702}; KW Reference proteome {ECO:0000313|Proteomes:UP000233180}; KW Secreted {ECO:0000256|SAAS:SAAS00509699}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 24 {ECO:0000256|SAM:SignalP}. FT CHAIN 25 381 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5014402023. FT DOMAIN 22 94 IGFBP N-terminal. {ECO:0000259|PROSITE: FT PS51323}. FT DOMAIN 98 164 VWFC. {ECO:0000259|PROSITE:PS50184}. FT DOMAIN 286 360 CTCK. {ECO:0000259|PROSITE:PS01225}. SQ SEQUENCE 381 AA; 41995 MW; B8F4EE0A52C3F635 CRC64; MSSRIARALA LAVTLLHLIR LSLSTCPAAC HCPLEAPKCA PGVGLVRDGC GCCKVCAKQL NEDCSKTQPC DHTKGLECNF GASSTALKGI CRAQSEGRPC EYNSRIYQNG ESFQPNCKHQ CTCIDGAVGC IPLCPQELSL PNLGCPNPRL VKVTGQCCEE WVCDEDSVKD PMDDQEGLLG KELGFDASEV ELTRNNELIA VGKGSSLKRL PVFGMEPRIL YNPLHGQKCI VQTTSWSQCS KTCGTGISTR VTNDNPECRL VKETRICEVR PCGQPVYSSL KKGKKCSKTK KSPEPVRFTY AGCSSVKKYR PKYCGSCVDG RCCTPQLTRT VKMRFRCEDG ETFSKNVMMI QSCKCNYNCP HANEAAFPFY RLFNDIHKFR D //