ID A0A2K6DCQ5_MACNE Unreviewed; 383 AA. AC A0A2K6DCQ5; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 13-NOV-2019, entry version 10. DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394}; GN Name=KIF25 {ECO:0000313|Ensembl:ENSMNEP00000033691}; OS Macaca nemestrina (Pig-tailed macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000033691, ECO:0000313|Proteomes:UP000233120}; RN [1] {ECO:0000313|Ensembl:ENSMNEP00000033691, ECO:0000313|Proteomes:UP000233120} RP NUCLEOTIDE SEQUENCE. RA Hughes D.S., Liu Y., Murali S., Raveendran M., Korchina V., Wang M., RA Jhangiani S., Bandaranaike D., Bellair M., Blankenburg K., Chao H., RA Dahdouli M., Dinh H., Doddapaneni H., English A., Gnanaolivu R., RA Gross S., Jayaseelan J., Jones J., Khan Z., Kovar C., Kurapati P., RA Le B., Lee S., Matakis S., Mathew T., Narasimhan A., Ngo D., RA Okwuonu G., Ongeri F., Osuji N., Otenyo P., Patel E., Qu C., RA Quiroz J., Raj R., Rajbhandari K., Reid J.G., Santibanez J., RA Skinner E., Vee V., Wang Y., Weissenberger G., Xin Y., Zou X., Han Y., RA Muzny D.M., Richards S., Worley K.C., Rogers J., Gibbs R.A.; RT "Pig-tailed Macaque reference genome and diversity panel."; RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSMNEP00000033691} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2018) to UniProtKB. CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase CC superfamily. Kinesin family. {ECO:0000256|PROSITE- CC ProRule:PRU00283, ECO:0000256|RuleBase:RU000394, CC ECO:0000256|SAAS:SAAS00583243}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSMNET00000058138; ENSMNEP00000033691; ENSMNEG00000040085. DR GeneTree; ENSGT00940000162166; -. DR OMA; VMLCISP; -. DR Proteomes; UP000233120; Whole Genome Shotgun Assembly. DR GO; GO:0005623; C:cell; IEA:GOC. DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0008017; F:microtubule binding; IEA:InterPro. DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro. DR GO; GO:0051294; P:establishment of spindle orientation; IEA:Ensembl. DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro. DR GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl. DR GO; GO:0046603; P:negative regulation of mitotic centrosome separation; IEA:Ensembl. DR GO; GO:0051647; P:nucleus localization; IEA:Ensembl. DR Gene3D; 3.40.850.10; -; 1. DR InterPro; IPR027640; Kinesin-like_fam. DR InterPro; IPR019821; Kinesin_motor_CS. DR InterPro; IPR001752; Kinesin_motor_dom. DR InterPro; IPR036961; Kinesin_motor_dom_sf. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR24115; PTHR24115; 1. DR Pfam; PF00225; Kinesin; 1. DR PRINTS; PR00380; KINESINHEAVY. DR SMART; SM00129; KISc; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS00411; KINESIN_MOTOR_1; 1. DR PROSITE; PS50067; KINESIN_MOTOR_2; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283, KW ECO:0000256|RuleBase:RU000394, ECO:0000256|SAAS:SAAS00875240}; KW Complete proteome {ECO:0000313|Proteomes:UP000233120}; KW Microtubule {ECO:0000256|RuleBase:RU000394}; KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283, KW ECO:0000256|RuleBase:RU000394}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283, KW ECO:0000256|RuleBase:RU000394, ECO:0000256|SAAS:SAAS00874078}; KW Reference proteome {ECO:0000313|Proteomes:UP000233120}. FT DOMAIN 1 362 Kinesin motor. {ECO:0000259|PROSITE: FT PS50067}. FT NP_BIND 64 71 ATP. {ECO:0000256|PROSITE-ProRule: FT PRU00283}. FT REGION 216 257 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 361 383 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 383 AA; 40635 MW; DC33BA09325F56DF CRC64; MKTSGQLPHE KQARPGSEAV LAFPDETDLR VYGPAESQSA VFGDVCPLLT SLLDGYNVCV MAYGQTGSGK SYTMLGPHSD DGPVLPLDPQ SDLGIIPRAA EELFRLISEN PSRSPKVEVS IVEVYNNDIF DLLAKDTVAA VSGVKREVMT AKDGRTEVAL LASEAVGSAS KLMELVRGGL QLRAKHPTLV HADSSRSHLI ITVTLTTAAC SDSTADQACS ATLPREQTEA GRAGRSRRTS QGASAPQPVP GDPAGRAEQV QARLQLVDLA GSECIGVSGV TGSALRETAC INRSLAALAD VLGALSEHRS HIPYRNSRLT HLLQDCLGGD AKLLVILCIS PSQRHLAQTL QGLGFGIRAR QVQRGPARKR PPSSQMEGKR RPD //