ID A0A2K5YDJ1_MANLE Unreviewed; 274 AA. AC A0A2K5YDJ1; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 10-FEB-2021, entry version 16. DE RecName: Full=Junctional adhesion molecule 1 {ECO:0000256|ARBA:ARBA00016620}; DE AltName: Full=Junctional adhesion molecule A {ECO:0000256|ARBA:ARBA00016608}; GN Name=F11R {ECO:0000313|Ensembl:ENSMLEP00000013643}; OS Mandrillus leucophaeus (Drill) (Papio leucophaeus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Mandrillus. OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000013643, ECO:0000313|Proteomes:UP000233140}; RN [1] {ECO:0000313|Ensembl:ENSMLEP00000013643} RP NUCLEOTIDE SEQUENCE. RA Murali S., Hughes D.S., Raveendran M., Korchina V., Bandaranaike D., RA Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H., Doddapaneni H., RA Gnanaolivu R., Gross S., Jayaseelan J., Khan Z., Kovar C., Kurapati P., RA Le B., Lee S., Mathew T., Narasimhan A., Okwuonu G., Ongeri F., Osuji N., RA Qu C., Quiroz J., Rajbhandari K., Reid J.G., Santibanez J., Skinner E., RA Wang Y., Xin Y., Han Y., Muzny D.M., Richards S., Worley K.C., Rogers J., RA Gibbs R.A.; RT "Drill reference genome project."; RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSMLEP00000013643} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2018) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction CC {ECO:0000256|ARBA:ARBA00004435}. Cell membrane CC {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein CC {ECO:0000256|ARBA:ARBA00004251}. Membrane CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein CC {ECO:0000256|ARBA:ARBA00004479}. CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CC {ECO:0000256|ARBA:ARBA00008637}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSMLET00000037084; ENSMLEP00000013643; ENSMLEG00000030976. DR GeneTree; ENSGT00940000159186; -. DR Proteomes; UP000233140; Unplaced. DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0007155; P:cell adhesion; IEA:InterPro. DR Gene3D; 2.60.40.10; -; 1. DR InterPro; IPR042456; F11R. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR003598; Ig_sub2. DR InterPro; IPR013151; Immunoglobulin. DR PANTHER; PTHR45113; PTHR45113; 1. DR Pfam; PF00047; ig; 1. DR SMART; SM00409; IG; 2. DR SMART; SM00408; IGc2; 2. DR SUPFAM; SSF48726; SSF48726; 2. DR PROSITE; PS50835; IG_LIKE; 1. PE 3: Inferred from homology; KW Cell junction {ECO:0000256|ARBA:ARBA00022949}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000233140}; KW Signal {ECO:0000256|ARBA:ARBA00022729}; KW Tight junction {ECO:0000256|ARBA:ARBA00022427}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 212..237 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 106..202 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" SQ SEQUENCE 274 AA; 29723 MW; 3E35769090C220A3 CRC64; WKFDQGDTTK LVCYNNKITG ELLLLLPDCL GCGGVIIALF TLSSPLPPLV VASYEDRVTF LPSGITFKSV TREDTGTYTC MVSEEGGNNY GEVKVKLIVL VPPSKPTVSI PSSATIGNRA VLTCSEKDGS PPSEYTWFKD GIVMPTNPKS TRAFSNSSYV LNPTTGELGE LGIGVRRPSD TGEYSCEARN GYGTPMTSNA VRMEGRLRQR NVGVIVAAVL VTLILLGILI FGIWFAYSRG HFDSKYLTSS KKVIYSQPSA RSEGEFKQTS SFLV //