ID A0A2J8RM60_PONAB Unreviewed; 292 AA. AC A0A2J8RM60; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 12-AUG-2020, entry version 10. DE SubName: Full=BRCC3 isoform 1 {ECO:0000313|EMBL:PNJ09616.1}; GN ORFNames=CR201_G0049981 {ECO:0000313|EMBL:PNJ09616.1}; OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Pongo. OX NCBI_TaxID=9601 {ECO:0000313|EMBL:PNJ09616.1, ECO:0000313|Proteomes:UP000236516}; RN [1] {ECO:0000313|EMBL:PNJ09616.1, ECO:0000313|Proteomes:UP000236516} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Susie {ECO:0000313|EMBL:PNJ09616.1}; RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M., RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J., RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M., RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B., RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.; RT "High-resolution comparative analysis of great ape genomes."; RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the peptidase M67A family. BRCC36 subfamily. CC {ECO:0000256|ARBA:ARBA00008021}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PNJ09616.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; NDHI03003672; PNJ09616.1; -; Genomic_DNA. DR RefSeq; XP_009233711.1; XM_009235436.1. DR SMR; A0A2J8RM60; -. DR GeneID; 100172840; -. DR CTD; 79184; -. DR OrthoDB; 968461at2759; -. DR Proteomes; UP000236516; Unassembled WGS sequence. DR GO; GO:0070531; C:BRCA1-A complex; IEA:InterPro. DR GO; GO:0070552; C:BRISC complex; IEA:InterPro. DR GO; GO:0004843; F:thiol-dependent ubiquitin-specific protease activity; IEA:InterPro. DR GO; GO:0006281; P:DNA repair; IEA:InterPro. DR GO; GO:0070536; P:protein K63-linked deubiquitination; IEA:InterPro. DR CDD; cd08068; MPN_BRCC36; 1. DR InterPro; IPR040749; BRCC36_C. DR InterPro; IPR000555; JAMM/MPN+_dom. DR InterPro; IPR037518; MPN. DR InterPro; IPR033860; MPN_BRCC36. DR Pfam; PF18110; BRCC36_C; 1. DR Pfam; PF01398; JAB; 1. DR SMART; SM00232; JAB_MPN; 1. DR PROSITE; PS50249; MPN; 1. PE 3: Inferred from homology; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Protease {ECO:0000256|ARBA:ARBA00022670}; KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}. FT DOMAIN 12..180 FT /note="MPN" FT /evidence="ECO:0000259|PROSITE:PS50249" FT COILED 260..292 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 292 AA; 33237 MW; 70302DC19999753C CRC64; MAVQVVQAVQ AVHLESDAFL VCLNHALSTE KEEVMGLCIG ELNDDTSRSD SKFAYTGTEM RTVAEKVDAV RIVHIHSVII LRRSDKRKDR VEISPEQLSA ASTEAERLAE LTGRPMRVVG WYHSHPHITV WPSHVDVRTQ AMYQMMDQGF VGLIFSCFIE DKNTKTGRVL YTCFQSIQAQ KSSEYERIEI PIHIVPHVTI GKVCLESAVE LPKILCQEEQ DAYRRIHSLT HLDSVTKIHN GSVFTKNLCS QMSAVSGPLL QWLEDRLEQN QQHLQELQQE KEELMQELSS LE //