ID A0A2I6SFE6_9POXV Unreviewed; 1164 AA. AC A0A2I6SFE6; DT 28-MAR-2018, integrated into UniProtKB/TrEMBL. DT 28-MAR-2018, sequence version 1. DT 23-MAY-2018, entry version 3. DE SubName: Full=Rpo132 {ECO:0000313|EMBL:AUO16289.1}; GN Name=EVH146 {ECO:0000313|EMBL:AUO16289.1}; OS Ectromelia virus. OC Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; OC Orthopoxvirus. OX NCBI_TaxID=12643 {ECO:0000313|EMBL:AUO16289.1}; RN [1] {ECO:0000313|EMBL:AUO16289.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Hamptead {ECO:0000313|EMBL:AUO16289.1}; RA Mavian C., Lopez-Bueno A., Alcami A.; RT "Comparative pathogenesis and genome sequence of ectromelia virus RT isolates from laboratory mouse outbreaks, or a wild mouse, and RT attenuated strains."; RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family. CC {ECO:0000256|RuleBase:RU000434}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KY554976; AUO16289.1; -; Genomic_DNA. DR RefSeq; NP_671646.1; NC_004105.1. DR GeneID; 951543; -. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro. DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro. DR Gene3D; 2.40.270.10; -; 3. DR Gene3D; 2.40.50.150; -; 2. DR InterPro; IPR015712; DNA-dir_RNA_pol_su2. DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom. DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf. DR InterPro; IPR024390; RNA_pol_132_poxvirus. DR InterPro; IPR007121; RNA_pol_bsu_CS. DR InterPro; IPR007645; RNA_pol_Rpb2_3. DR InterPro; IPR007647; RNA_pol_Rpb2_5. DR InterPro; IPR007641; RNA_pol_Rpb2_7. DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold. DR PANTHER; PTHR20856; PTHR20856; 1. DR Pfam; PF04565; RNA_pol_Rpb2_3; 1. DR Pfam; PF04567; RNA_pol_Rpb2_5; 1. DR Pfam; PF00562; RNA_pol_Rpb2_6; 1. DR Pfam; PF04560; RNA_pol_Rpb2_7; 1. DR Pfam; PF12415; rpo132; 1. DR PROSITE; PS01166; RNA_POL_BETA; 1. PE 3: Inferred from homology; FT DOMAIN 429 494 RNA_pol_Rpb2_3. {ECO:0000259|Pfam: FT PF04565}. FT DOMAIN 616 663 RNA_pol_Rpb2_5. {ECO:0000259|Pfam: FT PF04567}. FT DOMAIN 679 1047 RNA_pol_Rpb2_6. {ECO:0000259|Pfam: FT PF00562}. FT DOMAIN 1049 1141 RNA_pol_Rpb2_7. {ECO:0000259|Pfam: FT PF04560}. SQ SEQUENCE 1164 AA; 133429 MW; 81563DB6CB6DA3B6 CRC64; MKKNTDSEMD QRLGYKFLVP DPKAGVFYRP LHFQYVSYSN FILHRLHEIL TVKRPLLSFK NNTERIMIEI SNVKVTPPDY SPIIASIKGK SYDALATFTV NIFKEVMTKE GISITKISSY EGKDSHLIKI PLLIGYGNKN PLDTAKYLVP NVIGGVFINK QSVEKVGINL VEKITTWPKF RVVKPNSFTF SFSSVSPPNV LPTRYRHYKI SLDISQLEAS NISSTKTFIT VNIVLLSQYL SRVSLEFIRR SLSYDMPPEV VYLVNAIIDS AKRITESITD FNIDTYINDL VEAEHIKQKS QLTINEFKYE MLHNFLPHMN YTPDQLKGFY MISLLRKFLY CIYHTSRYPD RDSMVCHRIL TYGKYFETLA HDELENYIGN IRNDIMNNHK NRGTYAVNIH VLTTPGLNHA FSSLLSGKFK KSDGSYRTHP HYSWMQNISI PRSVGFYPDQ VKISKMFSVR KYHPSQYLYF CSSDVPERGP QVGLVSQLSV LSSITNILTS EYLDLEKKIC EYIRSYYKDD ISYFETGFPI TIENALVASL NPNMICDFVT DFRRRKRMGF FGNLEVGITL VRDHMNEIRI NIGAGRLVRP FLVVDNGELM MDVCQELESR LDDMTFSDIQ KEFPHVIEMV DIEQFTFSNV CESVQKFRMM SKDERKQYDL CDFPAEFRDG YVASSLVGIN HNSGPRAILG CAQAKQAISC LSSDIRNKID NGIHLMYPER PIVISKALET SKIAANCFGQ HVTIALMSYK GINQEDGIII KKQFIQRGGL DIVTAKKHQV EIPLENFNNK ERDRSNAYSK LESNGLVRLN AFLESGDAMA RNISSRTLED DFARDNQISF DVSEKYTDMY KSRVERVQVE LTDKVKVRVL TMKERRPILG DKFTTRTSQK GTVAYIADET ELPYDENGIT PDVIINSTSI FSRKTISMLI EVILTAAYSA KPYNNNGENR PVCFPSSNET SIDTYMQFAK QCYEHSNPQL TDDELSDKVF CEKILYDPET DKPYASKVFF GPIYYLRLRH LTQDKATVRC RGKKTKLIRQ ANEGRKRGGG IKFGEMERDC LIAHGAANTI TEVLKDSEED YQDVYICENC GDIAAQIKGI NTCLRCSKLN LSPLLTKIDT THVSKVFLTQ MNARGVKVKL DFERRPPSFY KQLDKVDLKP SFLK //