ID A0A2I4CSA7_9TELE Unreviewed; 1188 AA. AC A0A2I4CSA7; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 16-OCT-2019, entry version 10. DE SubName: Full=fragile X mental retardation syndrome-related protein 1 homolog B-like isoform X1 {ECO:0000313|RefSeq:XP_013882874.1}; GN Name=LOC106531534 {ECO:0000313|RefSeq:XP_013882874.1}; OS Austrofundulus limnaeus. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; OC Austrofundulus. OX NCBI_TaxID=52670 {ECO:0000313|Proteomes:UP000192220, ECO:0000313|RefSeq:XP_013882874.1}; RN [1] {ECO:0000313|RefSeq:XP_013882874.1} RP IDENTIFICATION. RC STRAIN=Quisiro {ECO:0000313|RefSeq:XP_013882874.1}; RC TISSUE=Liver {ECO:0000313|RefSeq:XP_013882874.1}; RG RefSeq; RL Submitted (JAN-2018) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_013882874.1; XM_014027420.1. DR GeneID; 106531534; -. DR KEGG; alim:106531534; -. DR OrthoDB; 374073at2759; -. DR Proteomes; UP000192220; Genome assembly. DR GO; GO:0003729; F:mRNA binding; IEA:InterPro. DR GO; GO:0006417; P:regulation of translation; IEA:InterPro. DR Gene3D; 1.25.40.10; -; 1. DR Gene3D; 3.30.1370.10; -; 2. DR InterPro; IPR008395; Agenet-like_dom. DR InterPro; IPR040148; FMR1. DR InterPro; IPR040472; FMRP_KH0. DR InterPro; IPR022034; FXMRP1_C_core. DR InterPro; IPR032172; FXR_C1. DR InterPro; IPR032177; FXR_C3. DR InterPro; IPR004087; KH_dom. DR InterPro; IPR004088; KH_dom_type_1. DR InterPro; IPR036612; KH_dom_type_1_sf. DR InterPro; IPR012340; NA-bd_OB-fold. DR InterPro; IPR022967; S1_dom. DR InterPro; IPR003029; S1_domain. DR InterPro; IPR013026; TPR-contain_dom. DR InterPro; IPR011990; TPR-like_helical_dom_sf. DR InterPro; IPR019734; TPR_repeat. DR InterPro; IPR041560; Tudor_FRX1. DR PANTHER; PTHR10603; PTHR10603; 2. DR Pfam; PF05641; Agenet; 1. DR Pfam; PF12235; FXMRP1_C_core; 1. DR Pfam; PF16096; FXR_C1; 1. DR Pfam; PF16097; FXR_C3; 1. DR Pfam; PF00013; KH_1; 2. DR Pfam; PF17904; KH_9; 1. DR Pfam; PF18336; Tudor_FRX1; 1. DR SMART; SM00322; KH; 2. DR SMART; SM00316; S1; 1. DR SMART; SM00028; TPR; 3. DR SUPFAM; SSF48452; SSF48452; 1. DR SUPFAM; SSF50249; SSF50249; 1. DR SUPFAM; SSF54791; SSF54791; 2. DR PROSITE; PS51641; AGENET_LIKE; 2. DR PROSITE; PS50126; S1; 1. DR PROSITE; PS50005; TPR; 3. DR PROSITE; PS50293; TPR_REGION; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000192220}; KW Reference proteome {ECO:0000313|Proteomes:UP000192220}; KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}. FT DOMAIN 118 200 S1 motif. {ECO:0000259|PROSITE:PS50126}. FT DOMAIN 299 407 TPR_REGION. {ECO:0000259|PROSITE: FT PS50293}. FT REPEAT 299 332 TPR. {ECO:0000256|PROSITE-ProRule: FT PRU00339}. FT REPEAT 333 366 TPR. {ECO:0000256|PROSITE-ProRule: FT PRU00339}. FT REPEAT 374 407 TPR. {ECO:0000256|PROSITE-ProRule: FT PRU00339}. FT DOMAIN 458 504 Agenet-like. {ECO:0000259|PROSITE: FT PS51641}. FT DOMAIN 517 569 Agenet-like. {ECO:0000259|PROSITE: FT PS51641}. FT REGION 877 1188 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 810 837 {ECO:0000256|SAM:Coils}. FT COMPBIAS 879 899 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 903 919 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 945 985 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 1018 1038 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1039 1059 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 1063 1077 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1118 1135 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 1141 1168 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 1188 AA; 133364 MW; 35CBD62A0C54D2AD CRC64; MDRDLLRQSL IFHGQSLFNK LKCEQTENPD FQAVVSDLSK ATYESRGEEQ DGSLVEQFIA RKADILFCPS WKTANPHEQE HEDEEAGEPY AIMPPVEVFM ELPYEERRAM IYRDLEKGDI VVGRINNIRE YGFFLTLLCM AGGLKRDIED LELSALCHIR EIPSSSSHDD PLSYYQVGDL IRGGVKDIDR YQEKITVSLH QACLSSSLEH IKLGVITREE LPIHYSRSVS AASDSSETYG CILTRCHGYE NPSVVEYLLE KVGISDTHPP SMMRGLQCKL FQEGDFASVI RKKQSASWAL KCVRAGVDHF KHGRHVEAMN EYNKALDIDL NNVEALVARG ALYANKGSIM KAISDFELAL ENCPDHRNAK KYLCQTLVEQ GKQLEEQEKL VTAEGLYRRA LSLDDSNPEA KEAMHNITET IQHFLVRALK PLNNNLTPDS FRNTCRPSIL CVSNMEELAV EVRGSNGAYY KGFVKDIHDD SLTIAFENNW QPERQVPFSD VRLPPPADAK KDIGEGEEVE IFSRANEQEP CGWWLAKVRM MKGDFYVIEY AACDATYNEI VTFERLRPVN TNKAVTKNSF HKCTVPVPQD LQEACQNENA HKEFKKAVGA CRISYCPETS ELLIVSTNDT TVKRVSLLSD MHLRSLRTKL LLMSRNQEAT KHLETSRQLV SSFQQEFTVR TDLMGLAIGS HGSNIQQARR VAGVTAIELD EETGTFRIYG ETEEAVKKAR NYLEFVEDSV QVPRNLVGKV IGKNGKVIQE IVDKSGVVRV KIEGDNDNKQ ARQETQGMVP FTFVGTKESI GNVQVLLEYH ISYLNDMAEL LAESQQLEED LKKVVDYTQG GSLARFRISC TRRTGCDVDE VEELRLERMQ IDEQLRQVTQ GHRAVDRERG DRGDRGERGA YNTDSGANAS SSISGSRSYN GRGRGRRGYN YNTGYGTNSE QSNASETDSE RKEELSDWSL AGEDQDGERE RGSRPQRDGR RRPGPGRGRG GPGGRGRGGR GGYSNSYAPR DQENYHPYGT MEANTETDQT ADTDASESNL PANRRRRSRR RRTDEDATLI DGMSESDNAS VSENGTERSE AKPQRRNRSR RRRNRLPEER QPVTVADYIS RAESQSRQMM AKDTKKNKDV GQVEVIDEHS PQSVPPTTNG SNNGVSDTSS SSATKAPRSS ADKPAEVSSP QPVLNGLS //