ID A0A2I3M785_PAPAN Unreviewed; 323 AA. AC A0A2I3M785; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 25-MAY-2022, sequence version 2. DT 12-OCT-2022, entry version 19. DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; OS Papio anubis (Olive baboon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Papio. OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000031518, ECO:0000313|Proteomes:UP000028761}; RN [1] {ECO:0000313|Ensembl:ENSPANP00000031518, ECO:0000313|Proteomes:UP000028761} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A., RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B., RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B., RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C., RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D., RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F., RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G., RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H., RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J., RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L., RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L., RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M., RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N., RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O., RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P., RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R., RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S., RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T., RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V., RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W., RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.; RT "Whole Genome Assembly of Papio anubis."; RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPANP00000031518} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2018) to UniProtKB. CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA- CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:83421; EC=3.1.3.16; CC Evidence={ECO:0000256|ARBA:ARBA00001512}; CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA- CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:61977; EC=3.1.3.16; CC Evidence={ECO:0000256|ARBA:ARBA00001482, CC ECO:0000256|RuleBase:RU004273}; CC -!- COFACTOR: CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; CC Evidence={ECO:0000256|ARBA:ARBA00001936}; CC -!- SUBCELLULAR LOCATION: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. CC Cytoplasm, cytoskeleton, microtubule organizing center CC {ECO:0000256|ARBA:ARBA00004267}. Midbody CC {ECO:0000256|ARBA:ARBA00004214}. Nucleus, nucleolus CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm CC {ECO:0000256|ARBA:ARBA00004642}. CC -!- SIMILARITY: Belongs to the PPP phosphatase family. PP-1 subfamily. CC {ECO:0000256|ARBA:ARBA00005333}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR SMR; A0A2I3M785; -. DR Ensembl; ENSPANT00000031115.2; ENSPANP00000031518.2; ENSPANG00000016506.3. DR GeneTree; ENSGT00940000153472; -. DR Proteomes; UP000028761; Chromosome 9. DR Bgee; ENSPANG00000016506; Expressed in testis and 66 other tissues. DR ExpressionAtlas; A0A2I3M785; baseline. DR GO; GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell. DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. DR GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell. DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0000164; C:protein phosphatase type 1 complex; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW. DR GO; GO:0006470; P:protein dephosphorylation; IEA:UniProt. DR Gene3D; 3.60.21.10; -; 1. DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH. DR InterPro; IPR029052; Metallo-depent_PP-like. DR InterPro; IPR037981; PPP1CC. DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase. DR InterPro; IPR031675; STPPase_N. DR PANTHER; PTHR11668:SF204; PTHR11668:SF204; 1. DR Pfam; PF00149; Metallophos; 1. DR Pfam; PF16891; STPPase_N; 1. DR PRINTS; PR00114; STPHPHTASE. DR SMART; SM00156; PP2Ac; 1. DR SUPFAM; SSF56300; SSF56300; 1. DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277}; KW Cell cycle {ECO:0000256|ARBA:ARBA00022618}; KW Cell division {ECO:0000256|ARBA:ARBA00022618}; KW Glycogen metabolism {ECO:0000256|ARBA:ARBA00022600}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004273}; KW Manganese {ECO:0000256|ARBA:ARBA00023211}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912}; KW Reference proteome {ECO:0000313|Proteomes:UP000028761}. FT DOMAIN 121..126 FT /note="SER_THR_PHOSPHATASE" FT /evidence="ECO:0000259|PROSITE:PS00125" FT REGION 302..323 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 323 AA; 36984 MW; 0EEEF0E842188536 CRC64; MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKK //