ID A0A2I3M785_PAPAN Unreviewed; 314 AA. AC A0A2I3M785; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 10-FEB-2021, entry version 12. DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; GN Name=PPP1CC {ECO:0000313|Ensembl:ENSPANP00000031518}; OS Papio anubis (Olive baboon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Papio. OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000031518, ECO:0000313|Proteomes:UP000028761}; RN [1] {ECO:0000313|Ensembl:ENSPANP00000031518, ECO:0000313|Proteomes:UP000028761} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A., RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B., RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B., RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C., RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D., RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F., RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G., RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H., RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J., RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L., RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L., RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M., RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N., RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O., RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P., RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R., RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S., RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T., RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V., RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W., RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.; RT "Whole Genome Assembly of Papio anubis."; RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPANP00000031518} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2018) to UniProtKB. CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA- CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:83421; EC=3.1.3.16; CC Evidence={ECO:0000256|ARBA:ARBA00001512}; CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA- CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:61977; EC=3.1.3.16; CC Evidence={ECO:0000256|ARBA:ARBA00001482, CC ECO:0000256|RuleBase:RU004273}; CC -!- COFACTOR: CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; CC Evidence={ECO:0000256|ARBA:ARBA00001936}; CC -!- SUBCELLULAR LOCATION: Cleavage furrow {ECO:0000256|ARBA:ARBA00004626}. CC Midbody {ECO:0000256|ARBA:ARBA00004214}. Nucleus, nucleolus CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm CC {ECO:0000256|ARBA:ARBA00004642}. CC -!- SIMILARITY: Belongs to the PPP phosphatase family. CC {ECO:0000256|RuleBase:RU004273}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AHZZ02002975; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSPANT00000031115; ENSPANP00000031518; ENSPANG00000016506. DR GeneTree; ENSGT00940000153472; -. DR Proteomes; UP000028761; Chromosome 11. DR ExpressionAtlas; A0A2I3M785; baseline. DR GO; GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell. DR GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell. DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0000164; C:protein phosphatase type 1 complex; IEA:InterPro. DR GO; GO:0106306; F:protein serine phosphatase activity; IEA:UniProtKB-EC. DR GO; GO:0106307; F:protein threonine phosphatase activity; IEA:UniProtKB-EC. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW. DR Gene3D; 3.60.21.10; -; 1. DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH. DR InterPro; IPR029052; Metallo-depent_PP-like. DR InterPro; IPR037981; PPP1CC. DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase. DR InterPro; IPR031675; STPPase_N. DR PANTHER; PTHR11668:SF204; PTHR11668:SF204; 1. DR Pfam; PF00149; Metallophos; 1. DR Pfam; PF16891; STPPase_N; 1. DR PRINTS; PR00114; STPHPHTASE. DR SMART; SM00156; PP2Ac; 1. DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277}; KW Cell cycle {ECO:0000256|ARBA:ARBA00022618}; KW Cell division {ECO:0000256|ARBA:ARBA00022618}; KW Glycogen metabolism {ECO:0000256|ARBA:ARBA00022600}; KW Hydrolase {ECO:0000256|RuleBase:RU004273}; KW Manganese {ECO:0000256|ARBA:ARBA00023211}; KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912}; KW Reference proteome {ECO:0000313|Proteomes:UP000028761}. FT DOMAIN 112..117 FT /note="SER_THR_PHOSPHATASE" FT /evidence="ECO:0000259|PROSITE:PS00125" FT REGION 293..314 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 314 AA; 35946 MW; 838B56F857B5B2A6 CRC64; IFLPIYLNLV LGSKPGKNVQ LQENEIRGLC LKSREIFLSQ PILLELEAPL KICGDIHGQY YDLLRLFEYG GFPPESNYLF LGDYVDRGKQ SLETICLLLA YKIKYPENFF LLRGNHECAS INRIYGFYDE CKRRYNIKLW KTFTDCFNCL PIAAIVDEKI FCCHGGLSPD LQSMEQIRRI MRPTDVPDQG LLCDLLWSDP DKDVLGWGEN DRGVSFTFGA EVVAKFLHKH DLDLICRAHQ VVEDGYEFFA KRQLVTLFSA PNYCGEFDNA GAMMSVDETL MCSFQILKPA EKKKPNATRP VTPPRGMITK QAKK //