ID A0A2I3BQF8_MOUSE Unreviewed; 68 AA. AC A0A2I3BQF8; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 24-JAN-2024, entry version 28. DE SubName: Full=Frizzled class receptor 6 {ECO:0000313|Ensembl:ENSMUSP00000154162.2}; GN Name=Fzd6 {ECO:0000313|Ensembl:ENSMUSP00000154162.2, GN ECO:0000313|MGI:MGI:108474}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000154162.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000154162.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000154162.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000154162.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000154162.2}; RG Ensembl; RL Submitted (JUL-2023) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A2I3BQF8; -. DR SMR; A0A2I3BQF8; -. DR Antibodypedia; 2906; 373 antibodies from 37 providers. DR Ensembl; ENSMUST00000228491.2; ENSMUSP00000154162.2; ENSMUSG00000022297.16. DR AGR; MGI:108474; -. DR MGI; MGI:108474; Fzd6. DR VEuPathDB; HostDB:ENSMUSG00000022297; -. DR GeneTree; ENSGT00940000158485; -. DR ChiTaRS; Fzd6; mouse. DR Proteomes; UP000000589; Chromosome 15. DR Bgee; ENSMUSG00000022297; Expressed in lip and 144 other cell types or tissues. DR ExpressionAtlas; A0A2I3BQF8; baseline and differential. DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 1. DR InterPro; IPR015526; Frizzled/SFRP. DR InterPro; IPR036790; Frizzled_dom_sf. DR PANTHER; PTHR11309; FRIZZLED; 1. DR PANTHER; PTHR11309:SF75; FRIZZLED-6; 1. DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1. PE 4: Predicted; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473}; KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040}; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Receptor {ECO:0000256|ARBA:ARBA00023170}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transducer {ECO:0000256|ARBA:ARBA00023040}; KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}. FT SIGNAL 1..18 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 19..68 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5014169897" SQ SEQUENCE 68 AA; 7655 MW; 9DE0323D1C897F4E CRC64; MERSPFLLAC ILLPLVRGHS LFTCEPITVP RCMKMTYNMT FFPNLMGHYD QGIAAVEMGN FCGLELAI //