ID A0A2I3BQF8_MOUSE Unreviewed; 68 AA. AC A0A2I3BQF8; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 14-DEC-2022, entry version 22. DE SubName: Full=Frizzled-6 {ECO:0000313|Ensembl:ENSMUSP00000154162.2}; GN Name=Fzd6 {ECO:0000313|Ensembl:ENSMUSP00000154162.2, GN ECO:0000313|MGI:MGI:108474}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000154162.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000154162.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000154162.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000154162.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000154162.2}; RG Ensembl; RL Submitted (AUG-2022) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A2I3BQF8; -. DR SMR; A0A2I3BQF8; -. DR Antibodypedia; 2906; 348 antibodies from 36 providers. DR Ensembl; ENSMUST00000228491.2; ENSMUSP00000154162.2; ENSMUSG00000022297.16. DR AGR; MGI:108474; -. DR MGI; MGI:108474; Fzd6. DR VEuPathDB; HostDB:ENSMUSG00000022297; -. DR GeneTree; ENSGT00940000158485; -. DR ChiTaRS; Fzd6; mouse. DR Proteomes; UP000000589; Chromosome 15. DR Bgee; ENSMUSG00000022297; Expressed in lip and 141 other tissues. DR ExpressionAtlas; A0A2I3BQF8; baseline and differential. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0042813; F:Wnt receptor activity; IEA:InterPro. DR Gene3D; 1.10.2000.10; -; 1. DR InterPro; IPR015526; Frizzled/SFRP. DR InterPro; IPR036790; Frizzled_dom_sf. DR InterPro; IPR026543; FZD6. DR PANTHER; PTHR11309; FRIZZLED; 1. DR PANTHER; PTHR11309:SF75; FRIZZLED-6; 1. DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..18 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 19..68 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5014169897" SQ SEQUENCE 68 AA; 7655 MW; 9DE0323D1C897F4E CRC64; MERSPFLLAC ILLPLVRGHS LFTCEPITVP RCMKMTYNMT FFPNLMGHYD QGIAAVEMGN FCGLELAI //