ID A0A2I2YB49_GORGO Unreviewed; 351 AA. AC A0A2I2YB49; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 23-MAY-2018, entry version 4. DE SubName: Full=Protein kinase cAMP-activated catalytic subunit alpha {ECO:0000313|Ensembl:ENSGGOP00000032040}; GN Name=PRKACA {ECO:0000313|Ensembl:ENSGGOP00000032040}; OS Gorilla gorilla gorilla (Western lowland gorilla). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Gorilla. OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000032040, ECO:0000313|Proteomes:UP000001519}; RN [1] {ECO:0000313|Ensembl:ENSGGOP00000032040, ECO:0000313|Proteomes:UP000001519} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Scally A.; RT "Insights into the evolution of the great apes provided by the gorilla RT genome."; RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSGGOP00000032040} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2018) to UniProtKB. CC -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. CC {ECO:0000256|SAAS:SAAS00935732}. CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CC {ECO:0000256|RuleBase:RU000304}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CABD030111917; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CABD030111918; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CABD030111919; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CABD030111920; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CABD030111921; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_004060204.1; XM_004060156.2. DR SMR; A0A2I2YB49; -. DR Ensembl; ENSGGOT00000060240; ENSGGOP00000032040; ENSGGOG00000013294. DR GeneID; 101133536; -. DR CTD; 5566; -. DR GeneTree; ENSGT00810000125385; -. DR Proteomes; UP000001519; Chromosome 19. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. DR InterPro; IPR000961; AGC-kinase_C. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00133; S_TK_X; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS51285; AGC_KINASE_CTER; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|RuleBase:RU000304, KW ECO:0000256|SAAS:SAAS00593399}; KW Complete proteome {ECO:0000313|Proteomes:UP000001519}; KW Kinase {ECO:0000256|SAAS:SAAS00593820}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU000304, KW ECO:0000256|SAAS:SAAS00593601}; KW Reference proteome {ECO:0000313|Proteomes:UP000001519}; KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304, KW ECO:0000256|SAAS:SAAS00593706}; KW Transferase {ECO:0000256|SAAS:SAAS00592725}. FT DOMAIN 44 298 Protein kinase. {ECO:0000259|PROSITE: FT PS50011}. FT DOMAIN 299 351 AGC-kinase C-terminal. FT {ECO:0000259|PROSITE:PS51285}. SQ SEQUENCE 351 AA; 40590 MW; BF6D3ECD2614E5AB CRC64; MGNAAAAKKG SEQESVKEFL AKAKEDFLKK WESPAQNTAH LDQFERIKTL GTGSFGRVML VKHKETGNHY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVKLEFS FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDQQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVN DIKNHKWFAT TDWIAIYQRK VEAPFIPKFK GPGDTSNFDD YEEEEIRVSI NEKCGKEFSE F //