ID A0A2I1GA78_9GLOM Unreviewed; 634 AA. AC A0A2I1GA78; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 16-JAN-2019, entry version 7. DE RecName: Full=Mitochondrial Rho GTPase {ECO:0000256|PIRNR:PIRNR037488}; DE EC=3.6.5.- {ECO:0000256|PIRNR:PIRNR037488}; GN ORFNames=RhiirA4_457518 {ECO:0000313|EMBL:PKY43522.1}; OS Rhizophagus irregularis. OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina; OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus. OX NCBI_TaxID=588596 {ECO:0000313|EMBL:PKY43522.1, ECO:0000313|Proteomes:UP000234323}; RN [1] {ECO:0000313|EMBL:PKY43522.1, ECO:0000313|Proteomes:UP000234323} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A4 {ECO:0000313|EMBL:PKY43522.1, RC ECO:0000313|Proteomes:UP000234323}; RA Ropars J., Sedzielewska K., Noel J., Charron P., Farinelli L., RA Marton T., Kruger M., Pelin A., Brachmann A., Corradi N.; RT "Genome analyses suggest a sexual origin of heterokaryosis in a RT supposedly ancient asexual fungus."; RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Mitochondrial GTPase involved in mitochondrial CC trafficking. {ECO:0000256|PIRNR:PIRNR037488}. CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane CC {ECO:0000256|PIRNR:PIRNR037488}; Single-pass type IV membrane CC protein {ECO:0000256|PIRNR:PIRNR037488}. CC -!- SIMILARITY: Belongs to the mitochondrial Rho GTPase family. CC {ECO:0000256|PIRNR:PIRNR037488}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:PKY43522.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LLXI01000259; PKY43522.1; -; Genomic_DNA. DR OrthoDB; 538388at2759; -. DR Proteomes; UP000234323; Unassembled WGS sequence. DR GO; GO:0031307; C:integral component of mitochondrial outer membrane; IEA:InterPro. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW. DR GO; GO:0003924; F:GTPase activity; IEA:InterPro. DR GO; GO:0007005; P:mitochondrion organization; IEA:InterPro. DR InterPro; IPR011992; EF-hand-dom_pair. DR InterPro; IPR018247; EF_Hand_1_Ca_BS. DR InterPro; IPR013566; EF_hand_assoc_1. DR InterPro; IPR013567; EF_hand_assoc_2. DR InterPro; IPR002048; EF_hand_dom. DR InterPro; IPR021181; Miro. DR InterPro; IPR020860; MIRO_dom. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR005225; Small_GTP-bd_dom. DR InterPro; IPR001806; Small_GTPase. DR Pfam; PF08355; EF_assoc_1; 1. DR Pfam; PF08356; EF_assoc_2; 1. DR Pfam; PF00071; Ras; 2. DR PIRSF; PIRSF037488; Mt_Rho_GTPase; 1. DR SMART; SM00054; EFh; 2. DR SUPFAM; SSF47473; SSF47473; 1. DR SUPFAM; SSF52540; SSF52540; 2. DR TIGRFAMs; TIGR00231; small_GTP; 1. DR PROSITE; PS00018; EF_HAND_1; 1. DR PROSITE; PS50222; EF_HAND_2; 2. DR PROSITE; PS51423; MIRO; 2. PE 3: Inferred from homology; KW Calcium {ECO:0000256|PIRNR:PIRNR037488, ECO:0000256|PROSITE- KW ProRule:PRU00448}; KW Complete proteome {ECO:0000313|Proteomes:UP000234323}; KW GTP-binding {ECO:0000256|PIRNR:PIRNR037488}; KW Hydrolase {ECO:0000256|PIRNR:PIRNR037488}; KW Membrane {ECO:0000256|PIRNR:PIRNR037488, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|PIRNR:PIRNR037488}; KW Mitochondrion outer membrane {ECO:0000256|PIRNR:PIRNR037488}; KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR037488}; KW Reference proteome {ECO:0000313|Proteomes:UP000234323}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 598 619 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 1 179 Miro. {ECO:0000259|PROSITE:PS51423}. FT DOMAIN 186 221 EF-hand. {ECO:0000259|PROSITE:PS50222}. FT DOMAIN 306 341 EF-hand. {ECO:0000259|PROSITE:PS50222}. FT DOMAIN 410 574 Miro. {ECO:0000259|PROSITE:PS51423}. FT CA_BIND 199 210 {ECO:0000256|PROSITE-ProRule:PRU00448}. SQ SEQUENCE 634 AA; 71269 MW; 8884F63D45D653A0 CRC64; MRREVRILLV GDDGVGKSTL ITSLIRETFV SELQHVVPEV TIPPEVTPEN VTTHIVDSSA RSDNREQLKT EIKKANVICI VYAIDNPHTF NRLASFWLPF IRSLGVNVPI VLVGNKIDLR GDQITNQSLE DEIIPIMNDF KEVETCVECS AKQPLNVSEV FYFAQKAVLH PTAPLYDSRE HVLKPACIEA LKRIFNLCDR DKDGVLNDDE LNEFQRKCFN APLQQQELEG VKEVVKEHEP AGVDDVGLTE LGFLFLHTLF IQRGRLETTW TVLRKFGYGD DLSLREDFLY PSFDVPHDCS VELSPLGYEF FTEIFQVFDK DKDGALKESE LAQLFSTSPG DPWANSDFPH TTITNDAGAV TLQGWLAQWS MTTLLDYKTT LSYLAYLGFE DDTRMALKVT RPRKADRKRN KVQRNVFLAY VFGAAGSGKT SLLKAFVNKP YTNGYTPTTR PFCAVNSVEI KGAEKYLVLQ EFGSKYEAEI LQNKRKMEAC DLLCFVFDSS DVNSFSYIVE LRKRHNLDNY PTVFVATKSD SDLVQQRNEV QPDVYCHDLG LSGPVSVSVK NHQTADLWNH LVGVAINPVP ATPGLAGSAH ESSKVKKYLT FTAVMGALGG AAFLGYRLYQ QQRGFGNISK RDIL //