ID A0A2I0U9D6_LIMLA Unreviewed; 558 AA. AC A0A2I0U9D6; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 10-OCT-2018, entry version 4. DE RecName: Full=Beta-hexosaminidase {ECO:0000256|PIRNR:PIRNR001093}; DE EC=3.2.1.52 {ECO:0000256|PIRNR:PIRNR001093}; GN ORFNames=llap_7024 {ECO:0000313|EMBL:PKU42669.1}; OS Limosa lapponica baueri. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; OC Coelurosauria; Aves; Neognathae; Charadriiformes; Scolopacidae; OC Limosa. OX NCBI_TaxID=1758121 {ECO:0000313|EMBL:PKU42669.1, ECO:0000313|Proteomes:UP000233556}; RN [1] {ECO:0000313|EMBL:PKU42669.1, ECO:0000313|Proteomes:UP000233556} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BTGAFAM01 {ECO:0000313|EMBL:PKU42669.1}; RC TISSUE=Blood {ECO:0000313|EMBL:PKU42669.1}; RA Han C.G.; RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000233556} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lima N.C.B., Parody-Merino A.M., Battley P.F., Fidler A.E., RA Prosdocimi F.; RT "Genome sequence of the Bar-tailed Godwit (Limosa lapponica baueri)."; RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Hydrolysis of terminal non-reducing N-acetyl- CC D-hexosamine residues in N-acetyl-beta-D-hexosaminides. CC {ECO:0000256|PIRNR:PIRNR001093}. CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family. CC {ECO:0000256|PIRNR:PIRNR001093}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KZ505970; PKU42669.1; -; Genomic_DNA. DR Proteomes; UP000233556; Unassembled WGS sequence. DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC. DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR Gene3D; 3.30.379.10; -; 1. DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub. DR InterPro; IPR015883; Glyco_hydro_20_cat. DR InterPro; IPR017853; Glycoside_hydrolase_SF. DR InterPro; IPR029018; Hex-like_dom2. DR InterPro; IPR029019; HEX_eukaryotic_N. DR Pfam; PF00728; Glyco_hydro_20; 1. DR Pfam; PF14845; Glycohydro_20b2; 1. DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk_; 1. DR PRINTS; PR00738; GLHYDRLASE20. DR SUPFAM; SSF51445; SSF51445; 1. DR SUPFAM; SSF55545; SSF55545; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000233556}; KW Disulfide bond {ECO:0000256|PIRSR:PIRSR001093-2}; KW Glycosidase {ECO:0000256|PIRNR:PIRNR001093}; KW Hydrolase {ECO:0000256|PIRNR:PIRNR001093}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 18 {ECO:0000256|SAM:SignalP}. FT CHAIN 19 558 Beta-hexosaminidase. {ECO:0000256|SAM: FT SignalP}. FT /FTId=PRO_5014190499. FT DOMAIN 52 178 Glycohydro_20b2. {ECO:0000259|Pfam: FT PF14845}. FT DOMAIN 200 516 Glyco_hydro_20. {ECO:0000259|Pfam: FT PF00728}. FT ACT_SITE 355 355 Proton donor. {ECO:0000256|PIRSR: FT PIRSR001093-1}. FT DISULFID 87 137 {ECO:0000256|PIRSR:PIRSR001093-2}. FT DISULFID 309 360 {ECO:0000256|PIRSR:PIRSR001093-2}. FT DISULFID 534 551 {ECO:0000256|PIRSR:PIRSR001093-2}. SQ SEQUENCE 558 AA; 62896 MW; DDC3972197437471 CRC64; MGLAGLLLGL FLVPAVLVST SLRHGVPPTE PEAPPELAEW ESVSGTVRED SLWPLPQWLR TSRRQLQLAP GRFQLVHGAG SSAGPGCGLL QDAFRRYYEY MFGQSRGRTW GRGPPGGLGG PELLELQVVI EAPDPGCNSY PHLASSEAYH LTVTEPVAIL KADEVWGALR GLETFSQLVH EDDYGSFLVN ESEIDDFPRF AHRGILLDTS RHYLPLKSIL TNLDAMAFNK FNVLHWHIVD DQSFPYQSIY FPELSDKGAY SYNHIYTPTD VRLVIEYARL RGIRVIPEFD TPGHTQSWGK GQKDLLTPCY SGKHPTGSFG PVNPILNTTY DFMTKFYKEI SNVFPDAYIH LGGDEVDFNC WKSNPDVREF MKQQGFGIDY AKLESYYIQK ILDIVSSNNK GYVVWQEVFD NKAQLKPDTV VQVWIGNNYA HELSSVTGAG FTAILSAPWY LDYISYGQDW KKYYSVEPLN FPGSEKQKKL LIGGEACLWG EFVDATNLTP RLWPRASAVG ERLWSSRNVT NLQDAYERLT NHRCRMLRRG IAAEPVFTGY CAHEARGQ //