ID A0A2H5WHE3_9BACT Unreviewed; 403 AA. AC A0A2H5WHE3; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 28-MAR-2018, entry version 2. DE SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:GBC88352.1}; DE EC=5.99.1.2 {ECO:0000313|EMBL:GBC88352.1}; GN Name=topA {ECO:0000313|EMBL:GBC88352.1}; GN ORFNames=HRbin13_00473 {ECO:0000313|EMBL:GBC88352.1}; OS bacterium HR13. OC Bacteria. OX NCBI_TaxID=2035408 {ECO:0000313|EMBL:GBC88352.1}; RN [1] {ECO:0000313|EMBL:GBC88352.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=HRbin13 {ECO:0000313|EMBL:GBC88352.1}; RA Kato S., Suzuki K.; RT "Metaegenomics of thermophilic ammonia-oxidizing enrichment culture."; RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:GBC88352.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BEHP01000028; GBC88352.1; -; Genomic_DNA. DR CDD; cd00186; TOP1Ac; 1. DR Gene3D; 1.10.290.10; -; 1. DR Gene3D; 1.10.460.10; -; 2. DR Gene3D; 2.70.20.10; -; 2. DR InterPro; IPR000380; Topo_IA. DR InterPro; IPR003601; Topo_IA_2. DR InterPro; IPR023406; Topo_IA_AS. DR InterPro; IPR013497; Topo_IA_cen. DR InterPro; IPR013824; Topo_IA_cen_sub1. DR InterPro; IPR013825; Topo_IA_cen_sub2. DR InterPro; IPR013826; Topo_IA_cen_sub3. DR InterPro; IPR023405; Topo_IA_core_domain. DR InterPro; IPR003602; Topo_IA_DNA-bd_dom. DR PANTHER; PTHR42785; PTHR42785; 1. DR Pfam; PF01131; Topoisom_bac; 1. DR PRINTS; PR00417; PRTPISMRASEI. DR SMART; SM00437; TOP1Ac; 1. DR SMART; SM00436; TOP1Bc; 1. DR SUPFAM; SSF56712; SSF56712; 1. DR PROSITE; PS00396; TOPOISOMERASE_I_PROK; 1. PE 4: Predicted; KW Isomerase {ECO:0000313|EMBL:GBC88352.1}. FT DOMAIN 1 61 TOP1Bc. {ECO:0000259|SMART:SM00436}. FT DOMAIN 105 354 TOP1Ac. {ECO:0000259|SMART:SM00437}. SQ SEQUENCE 403 AA; 46983 MW; 8457757FE3BBA2EC CRC64; MSAQFSRRVL DRLIGYKLSP FLWRDLKERG LSVGRVQSPT LRLIVERERQ IQNFKRKKYY YIKAEFVVDG VEFSAVFKQR FEKPSNAEPF MKKLKDVMFV VKSVSKEMQK EPPPKPFNTV SLQAEASKIL GISVDKVQKM AQKLYEEGLI TYPRTDSYRM NKEKAQEFMK YIERTYGKDY VGRLRKYKEK ALAWGAHECI RPTSLNKKPE SVLELKLWSL ISSRALASLS SNAIREKVLV VLLPLSDHTL EFTAEGCLLV FDGWTRIYPK EVKDRALPHL EEGQVIKPRR VYIEEMEVPP PPRYTEGSLV KTLENLGIGR PSTYATIIKT LKDRGYVVLE KGYLKPTETA FKVVDYLMEK FPHLMDYGFT KYMEDNLDAV EEGKKDWKEV VRESYKRVLN AKE //