ID A0A2H4WZT1_9GENT Unreviewed; 190 AA. AC A0A2H4WZT1; DT 28-FEB-2018, integrated into UniProtKB/TrEMBL. DT 28-FEB-2018, sequence version 1. DT 27-NOV-2024, entry version 22. DE RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 {ECO:0000256|ARBA:ARBA00029493}; GN Name=nad9 {ECO:0000313|EMBL:AUD38846.1}; OS Lasianthus sp. Kainulaninen et al. 17. OG Mitochondrion {ECO:0000313|EMBL:AUD38846.1}. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; lamiids; Gentianales; Rubiaceae; Rubioideae; Lasiantheae; OC Lasianthus. OX NCBI_TaxID=1406727 {ECO:0000313|EMBL:AUD38846.1}; RN [1] {ECO:0000313|EMBL:AUD38846.1} RP NUCLEOTIDE SEQUENCE. RA Rydin C., Wikstrom N., Bremer B.; RT "Conflicting results from mitochondrial genomic data challenge current RT views of Rubiaceae phylogeny."; RL Am. J. Bot. 104:1522-1532(2017). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain CC NADH dehydrogenase (Complex I) that is believed to belong to the CC minimal assembly required for catalysis. Complex I functions in the CC transfer of electrons from NADH to the respiratory chain. The immediate CC electron acceptor for the enzyme is believed to be ubiquinone. CC {ECO:0000256|ARBA:ARBA00003257}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 CC H(+)(out); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA- CC COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976, CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2; CC Evidence={ECO:0000256|ARBA:ARBA00000766}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein CC {ECO:0000256|ARBA:ARBA00004443}; Matrix side CC {ECO:0000256|ARBA:ARBA00004443}. CC -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family. CC {ECO:0000256|ARBA:ARBA00007569, ECO:0000256|RuleBase:RU003456}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KY638311; AUD38846.1; -; Genomic_DNA. DR AlphaFoldDB; A0A2H4WZT1; -. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC. DR FunFam; 3.30.460.80:FF:000005; NADH dehydrogenase subunit 9; 1. DR Gene3D; 3.30.460.80; NADH:ubiquinone oxidoreductase, 30kDa subunit; 1. DR HAMAP; MF_01357; NDH1_NuoC; 1. DR InterPro; IPR010218; NADH_DH_suC. DR InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like. DR InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su. DR InterPro; IPR020396; NADH_UbQ_OxRdtase_CS. DR PANTHER; PTHR10884:SF14; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL; 1. DR PANTHER; PTHR10884; NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3; 1. DR Pfam; PF00329; Complex1_30kDa; 1. DR SUPFAM; SSF143243; Nqo5-like; 1. DR PROSITE; PS00542; COMPLEX1_30K; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Mitochondrion {ECO:0000313|EMBL:AUD38846.1}; KW NAD {ECO:0000256|ARBA:ARBA00023027, ECO:0000256|RuleBase:RU003456}; KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU003456}; KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003456}. FT DOMAIN 35..152 FT /note="NADH:ubiquinone oxidoreductase 30kDa subunit" FT /evidence="ECO:0000259|Pfam:PF00329" SQ SEQUENCE 190 AA; 22681 MW; E06D457A64635168 CRC64; MDNQLIFKYS WETLPKKWVK KMERSEHGNR SDTNTDYLFQ LLCFLKFHTY TRVQVLIDIC GVDYPSRKRR FEVVYNLLST RYNSRIRVQT SADEVTRISP VVSLFPSAGR WEREVWDMFG VSSINHPDLR RISTDYGFEG HPLRKDLPLS GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF ASPWEQRSDG //