ID   A0A2E4SHK5_9GAMM        Unreviewed;       273 AA.
AC   A0A2E4SHK5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   25-MAY-2022, entry version 13.
DE   SubName: Full=Mechanosensitive ion channel protein {ECO:0000313|EMBL:MBF39282.1};
GN   ORFNames=CMF20_09535 {ECO:0000313|EMBL:MBF39282.1};
OS   Idiomarinaceae bacterium.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae.
OX   NCBI_TaxID=1898113 {ECO:0000313|EMBL:MBF39282.1, ECO:0000313|Proteomes:UP000231262};
RN   [1] {ECO:0000313|Proteomes:UP000231262}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC       {ECO:0000256|ARBA:ARBA00008017}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MBF39282.1}.
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DR   EMBL; PAYC01000029; MBF39282.1; -; Genomic_DNA.
DR   EnsemblBacteria; MBF39282; MBF39282; CMF20_09535.
DR   Proteomes; UP000231262; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008381; F:mechanosensitive ion channel activity; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR045275; MscS_archaea/bacteria_type.
DR   InterPro; IPR006685; MscS_channel.
DR   InterPro; IPR011066; MscS_channel_C.
DR   InterPro; IPR006686; MscS_channel_CS.
DR   InterPro; IPR011014; MscS_channel_TM-2.
DR   InterPro; IPR023408; MscS_dom_sf.
DR   InterPro; IPR008910; TM_helix.
DR   PANTHER; PTHR30221; PTHR30221; 1.
DR   Pfam; PF00924; MS_channel; 1.
DR   Pfam; PF05552; TM_helix; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   SUPFAM; SSF82689; SSF82689; 1.
DR   SUPFAM; SSF82861; SSF82861; 1.
DR   PROSITE; PS01246; UPF0003; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   273 AA;  30089 MW;  0FAF1D8DA99FCD9E CRC64;
     MDSIVQWIND NQDMLIEFSI KFIIAIAILI IGKIVANGVT RVMSKGMQKR EVDGAVISFV
     SAIVKTVIFI AAIMMALSHV GVETTSFIAI LGAAGLAIGL ALQGSLSNIA SGVLLIMFRP
     FRAGEYVDAG GVSGTVEQIN IFQTVLKTPD RKIIFVPNSE IIGGPITNYN REELRRIDLV
     IGVSYSANLQ KTKQVLMDVI TSDERVLKDP EPVVTVTELG ASSVDFNVRP WTKNEDYWPT
     RWDLLERIKD RLDEEGIGIP FPQMDVHLKK DDA
//