ID A0A2D9VNQ2_9RHOB Unreviewed; 262 AA. AC A0A2D9VNQ2; DT 31-JAN-2018, integrated into UniProtKB/TrEMBL. DT 31-JAN-2018, sequence version 1. DT 07-NOV-2018, entry version 6. DE RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH] {ECO:0000256|PIRNR:PIRNR000094}; DE EC=1.3.1.9 {ECO:0000256|PIRNR:PIRNR000094}; GN ORFNames=CL812_13545 {ECO:0000313|EMBL:MAQ46855.1}; OS Confluentimicrobium sp. OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales; OC Rhodobacteraceae; Confluentimicrobium. OX NCBI_TaxID=1931204 {ECO:0000313|EMBL:MAQ46855.1}; RN [1] {ECO:0000313|EMBL:MAQ46855.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=NAT9 {ECO:0000313|EMBL:MAQ46855.1}; RX PubMed=29337314; DOI=.1038/sdata.2017.203; RA Tully B.J., Graham E.D., Heidelberg J.F.; RT "The reconstruction of 2,631 draft metagenome-assembled genomes from RT the global oceans."; RL Sci. Data 5:170203-170203(2018). CC -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a CC trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH. CC {ECO:0000256|PIRNR:PIRNR000094}. CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases CC (SDR) family. FabI subfamily. {ECO:0000256|PIRNR:PIRNR000094}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:MAQ46855.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; NZUI01000022; MAQ46855.1; -; Genomic_DNA. DR GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC. DR GO; GO:0016631; F:enoyl-[acyl-carrier-protein] reductase activity; IEA:UniProtKB-EC. DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. DR InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR002347; SDR_fam. DR PANTHER; PTHR43159:SF2; PTHR43159:SF2; 1. DR PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1. DR PRINTS; PR00081; GDHRDH. DR SUPFAM; SSF51735; SSF51735; 1. PE 3: Inferred from homology; KW Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000094}; KW Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000094}; KW Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000094}; KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000094}; KW NAD {ECO:0000256|PIRNR:PIRNR000094, ECO:0000256|PIRSR:PIRSR000094-3}; KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR000094, KW ECO:0000313|EMBL:MAQ46855.1}. FT NP_BIND 20 21 NAD. {ECO:0000256|PIRSR:PIRSR000094-3}. FT NP_BIND 65 66 NAD. {ECO:0000256|PIRSR:PIRSR000094-3}. FT ACT_SITE 146 146 Proton acceptor. {ECO:0000256|PIRSR: FT PIRSR000094-1}. FT ACT_SITE 156 156 Proton acceptor. {ECO:0000256|PIRSR: FT PIRSR000094-1}. FT BINDING 14 14 NAD; via carbonyl oxygen. FT {ECO:0000256|PIRSR:PIRSR000094-3}. FT BINDING 41 41 NAD. {ECO:0000256|PIRSR:PIRSR000094-3}. FT BINDING 93 93 NAD; via carbonyl oxygen. FT {ECO:0000256|PIRSR:PIRSR000094-3}. FT BINDING 163 163 NAD. {ECO:0000256|PIRSR:PIRSR000094-3}. SQ SEQUENCE 262 AA; 27877 MW; D05268FF4D594003 CRC64; MAELMKGKRG LIMGVANERS IAWGIAKALA AEGAELAFSY QGESFGKRVA PLAESVGSDF LVDVDVTDDA SLDAAFGEIE KRWGKLDFVV HAIAFSDKNE LTGRFINTSR ENFKTSLVIS CYSLIDVARR ARPLMTDGGS IITLTYQGSN KVTPFYNVMG VAKSALESAM RYLANDLGPE GIRVNAISPG PMKTLAGAAI GGARKTFRMT EANAPLRHNA TLEAIGGTAV YLASDYGNCT TGEIVTVDGG FHILGMPQPD NL //