ID A0A2D0PS27_ICTPU Unreviewed; 358 AA. AC A0A2D0PS27; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 02-OCT-2024, entry version 22. DE SubName: Full=PKc_LIMK_like_unk domain-containing protein isoform X1 {ECO:0000313|RefSeq:XP_017307885.1}; GN Name=zgc:162952 {ECO:0000313|RefSeq:XP_017307885.1}; OS Ictalurus punctatus (Channel catfish) (Silurus punctatus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes; OC Ictaluridae; Ictalurus. OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017307885.1}; RN [1] {ECO:0000313|RefSeq:XP_017307885.1} RP IDENTIFICATION. RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017307885.1}; RG RefSeq; RL Submitted (JUN-2024) to UniProtKB. CC -!- SIMILARITY: Belongs to the protein kinase superfamily. TKL Ser/Thr CC protein kinase family. {ECO:0000256|ARBA:ARBA00005843}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_017307885.1; XM_017452396.3. DR AlphaFoldDB; A0A2D0PS27; -. DR Ensembl; ENSIPUT00015094412; ENSIPUP00015080233; ENSIPUG00015036348. DR GeneID; 108255974; -. DR KEGG; ipu:108255974; -. DR OrthoDB; 5474815at2759; -. DR Proteomes; UP000221080; Chromosome 22. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR CDD; cd14156; PKc_LIMK_like_unk; 1. DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1. DR InterPro; IPR050940; Actin_reg-Ser/Thr_kinase. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR PANTHER; PTHR46485; LIM DOMAIN KINASE 1; 1. DR PANTHER; PTHR46485:SF2; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1. DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1. DR PIRSF; PIRSF000654; Integrin-linked_kinase; 2. DR PRINTS; PR00109; TYRKINASE. DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141}. FT DOMAIN 88..355 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT BINDING 117 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141" SQ SEQUENCE 358 AA; 41042 MW; 15B11B57A9FE5ACA CRC64; MRERERETGR QTVGVYEWTC LSDAALNTQY LSHTEPALHA QIHRMCEVDV SSEPSSPTLY SESSDAYYHV DRWQKLRTAV RKLEFWENFS HELIGSGFFS KVYKVMHNNT RKVMVVKIYK NDVDQDSIVR EISLLQKLSH PNIVRYLGIC VKEDKLYPIL EYVSGGCLEE LLARKDVPLC WREKVDLSSD ITRGMIYLHY KNIYHRDLNS KNCLIRVTAR GREALVTDFG LAREVVELPA KDRKLSLVGS AFWMAPEMLR GEPYDRKVDV FSFGIVLCEI LARVPADPEI LPRTQDYGLD ASAFKKMAPG CPQRVLDLAS NCCLIEAFRR PSFTEVLDEL AEIAETLEPP THTELTTG //