ID A0A2C9XMW5_9ENTE Unreviewed; 231 AA. AC A0A2C9XMW5; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 03-MAY-2023, entry version 16. DE RecName: Full=VanC-type vancomycin resistance DNA-binding response regulator VanR {ECO:0000256|Google:ProtNLM}; GN ORFNames=A5870_002418 {ECO:0000313|EMBL:OTO35048.1}; OS Enterococcus sp. 2G9_DIV0600. OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; OC Enterococcus. OX NCBI_TaxID=1834173 {ECO:0000313|EMBL:OTO35048.1, ECO:0000313|Proteomes:UP000194585}; RN [1] {ECO:0000313|EMBL:OTO35048.1, ECO:0000313|Proteomes:UP000194585} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=2G9_DIV0600 {ECO:0000313|EMBL:OTO35048.1, RC ECO:0000313|Proteomes:UP000194585}; RG The Broad Institute Genomics Platform; RG The Broad Institute Genomic Center for Infectious Diseases; RA Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P., RA Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C., RA Birren B.; RT "The Genome Sequence of Enterococcus sp. 2G9_DIV0600."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OTO35048.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; NGLL01000001; OTO35048.1; -; Genomic_DNA. DR RefSeq; WP_034872470.1; NZ_NGLL01000001.1. DR AlphaFoldDB; A0A2C9XMW5; -. DR EnsemblBacteria; OTO35048; OTO35048; A5870_002418. DR Proteomes; UP000194585; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW. DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro. DR CDD; cd00383; trans_reg_C; 1. DR Gene3D; 3.40.50.2300; -; 1. DR Gene3D; 6.10.250.690; -; 1. DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd. DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR InterPro; IPR039420; WalR-like. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR PANTHER; PTHR48111; REGULATOR OF RPOS; 1. DR PANTHER; PTHR48111:SF2; RESPONSE REGULATOR SAER; 1. DR Pfam; PF00072; Response_reg; 1. DR Pfam; PF00486; Trans_reg_C; 1. DR SMART; SM00448; REC; 1. DR SMART; SM00862; Trans_reg_C; 1. DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1. DR SUPFAM; SSF52172; CheY-like; 1. DR PROSITE; PS51755; OMPR_PHOB; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU01091}; Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}; KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}. FT DOMAIN 4..117 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT DOMAIN 132..231 FT /note="OmpR/PhoB-type" FT /evidence="ECO:0000259|PROSITE:PS51755" FT DNA_BIND 132..231 FT /note="OmpR/PhoB-type" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091" FT MOD_RES 53 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" SQ SEQUENCE 231 AA; 26677 MW; 494FB41869936696 CRC64; MAEKIIVVDD EKEIAELVTT FLRNEGFQVE PFYDGTSALA YLEKETVDVA VLDVMLPDID GFQLLQTIRK THFFPVLMLT AKGEDLDKIT GLSLGADDYV TKPFNPLEVV ARVKTQLRRY QRYNQSAVPQ KIEEYEKEGL LLKINSHQCF LYGKEVFLTP IEFKILLYLF EHQGSVVASE TLFEAVWKEK YLDNNNTVMA HIARLREKLN EQPRKPKLIK TVWGVGYIIE K //