ID A0A2C6KFH6_9APIC Unreviewed; 224 AA. AC A0A2C6KFH6; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 25-MAY-2022, entry version 21. DE SubName: Full=Root hair defective 3 gtp-binding protein {ECO:0000313|EMBL:PHJ15418.1}; GN ORFNames=CSUI_010770 {ECO:0000313|EMBL:PHJ15418.1}; OS Cystoisospora suis. OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia; OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora. OX NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ15418.1, ECO:0000313|Proteomes:UP000221165}; RN [1] {ECO:0000313|EMBL:PHJ15418.1, ECO:0000313|Proteomes:UP000221165} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Wien I {ECO:0000313|EMBL:PHJ15418.1, RC ECO:0000313|Proteomes:UP000221165}; RX PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007; RA Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F., RA Blake D.P., Joachim A.; RT "The genome of the protozoan parasite Cystoisospora suis and a reverse RT vaccinology approach to identify vaccine candidates."; RL Int. J. Parasitol. 47:189-202(2017). CC -!- FUNCTION: Probable GTP-binding protein involved in generating and CC maintaining the structure of the tubular endoplasmic reticulum network. CC {ECO:0000256|ARBA:ARBA00029381}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase CC superfamily. GB1/RHD3 GTPase family. {ECO:0000256|PROSITE- CC ProRule:PRU01052}. CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase CC superfamily. Very large inducible GTPase (VLIG) family. CC {ECO:0000256|ARBA:ARBA00006828}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:PHJ15418.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MIGC01008244; PHJ15418.1; -; Genomic_DNA. DR VEuPathDB; ToxoDB:CSUI_010770; -. DR OrthoDB; 418635at2759; -. DR Proteomes; UP000221165; Unassembled WGS sequence. DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0005525; F:GTP binding; IEA:InterPro. DR Gene3D; 3.40.50.300; -; 1. DR InterPro; IPR030386; G_GB1_RHD3_dom. DR InterPro; IPR030383; G_VLIG_dom. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR008803; RHD3/Sey1. DR PANTHER; PTHR45923; PTHR45923; 1. DR Pfam; PF05879; RHD3; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS51715; G_GB1_RHD3; 1. DR PROSITE; PS51717; G_VLIG; 1. PE 3: Inferred from homology; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}; KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000221165}. FT DOMAIN 75..224 FT /note="GB1/RHD3-type G" FT /evidence="ECO:0000259|PROSITE:PS51715" FT DOMAIN 75..224 FT /note="VLIG-type G" FT /evidence="ECO:0000259|PROSITE:PS51717" FT REGION 1..41 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..21 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 224 AA; 24704 MW; 3C1F316207020597 CRC64; MELMNSPRTS SHQQGFSAPV PSSLLSPKEG ENNKKKKKHG EALDGGQLIQ IIDYEGDIVA DLDSWISKEK LRDVGFNFNV VTILGSQSSG KSSLMNALFG CNFQVMDHVH GHSQTTKGIW LGRDGFSRRL DENGIFSSSS SFSADSQGQE QPTLVVDVEG IDSRERGEDR QTFEHRSALF ALALADCLCI NVWYHSLGNF TASGYGLLKT VMQVNLELFA QQKK //