ID A0A288R3C1_9ERIC Unreviewed; 363 AA. AC A0A288R3C1; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 27-NOV-2024, entry version 19. DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic {ECO:0000256|HAMAP-Rule:MF_01350}; DE EC=7.1.1.- {ECO:0000256|HAMAP-Rule:MF_01350}; DE AltName: Full=NAD(P)H dehydrogenase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; DE Short=NDH subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; DE AltName: Full=NADH-plastoquinone oxidoreductase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350}; GN Name=ndhA {ECO:0000256|HAMAP-Rule:MF_01350, GN ECO:0000313|EMBL:APC61903.1}; OS Camellia pubipetala. OG Plastid; Chloroplast {ECO:0000313|EMBL:APC61903.1}. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; Ericales; Theaceae; Camellia. OX NCBI_TaxID=147930 {ECO:0000313|EMBL:APC61903.1}; RN [1] {ECO:0000313|EMBL:APC61903.1} RP NUCLEOTIDE SEQUENCE. RA Tang S., Liufu Y., Wei S., Chen H.; RT "Molecular taxonomy of yellow Camellias in China inferred from small single RT copy region and nrITS sequences."; RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:QPL15810.1} RP NUCLEOTIDE SEQUENCE. RA Fan Y., Zhao B.; RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:QSJ55628.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Leaf {ECO:0000313|EMBL:QSJ55628.1}; RA Tang S., Zheng H.; RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN CC and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain CC and possibly in a chloroplast respiratory chain. The immediate electron CC acceptor for the enzyme in this species is believed to be CC plastoquinone. Couples the redox reaction to proton translocation, and CC thus conserves the redox energy in a proton gradient. CC {ECO:0000256|HAMAP-Rule:MF_01350}. CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + NADH + (n+1) H(+)(in) = a plastoquinol + CC NAD(+) + n H(+)(out); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; CC -!- CATALYTIC ACTIVITY: CC Reaction=a plastoquinone + NADPH + (n+1) H(+)(in) = a plastoquinol + CC NADP(+) + n H(+)(out); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561, CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192; CC Evidence={ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which CC are encoded in the nucleus. {ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU000471}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU000471}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. Plastid, chloroplast thylakoid CC membrane {ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000474}; Multi-pass membrane protein CC {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}. CC -!- SIMILARITY: Belongs to the complex I subunit 1 family. CC {ECO:0000256|ARBA:ARBA00010535, ECO:0000256|HAMAP-Rule:MF_01350, CC ECO:0000256|RuleBase:RU000471}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KU669053; APC61903.1; -; Genomic_DNA. DR EMBL; MW186719; QPL15810.1; -; Genomic_DNA. DR EMBL; MW543444; QSJ55628.1; -; Genomic_DNA. DR AlphaFoldDB; A0A288R3C1; -. DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:TreeGrafter. DR GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-UniRule. DR GO; GO:0009060; P:aerobic respiration; IEA:TreeGrafter. DR GO; GO:0019684; P:photosynthesis, light reaction; IEA:UniProtKB-UniRule. DR HAMAP; MF_01350; NDH1_NuoH; 1. DR InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO. DR InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS. DR PANTHER; PTHR11432; NADH DEHYDROGENASE SUBUNIT 1; 1. DR PANTHER; PTHR11432:SF3; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1; 1. DR Pfam; PF00146; NADHdh; 1. DR PROSITE; PS00667; COMPLEX1_ND1_1; 1. DR PROSITE; PS00668; COMPLEX1_ND1_2; 1. PE 3: Inferred from homology; KW Chloroplast {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:APC61903.1}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01350}; KW NAD {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000471}; KW NADP {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Plastid {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:APC61903.1}; KW Plastoquinone {ECO:0000256|HAMAP-Rule:MF_01350, KW ECO:0000256|RuleBase:RU000474}; KW Quinone {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}; KW Translocase {ECO:0000256|HAMAP-Rule:MF_01350, KW ECO:0000256|RuleBase:RU000474}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP- KW Rule:MF_01350}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP- KW Rule:MF_01350}. FT TRANSMEM 26..50 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 97..116 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 122..147 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 255..277 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 297..322 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" FT TRANSMEM 343..361 FT /note="Helical" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01350, FT ECO:0000256|RuleBase:RU000474" SQ SEQUENCE 363 AA; 40236 MW; 8489A98110A2C279 CRC64; MIINTIEVQA INSFSRLESL KEVYGIIWMF VPILTLVLGI TIGVLVIVWL EREISAGIQQ RIGPEYAGPL GILQALADGT KLLFKENILP SRGDTRLFSI GPSIAVISIL LSYSIIPFGY RLILADLSIG VFLWIAISSI APVGLLMSGY GSNNKYSFLG GLRAAAQSIS YEIPLTLCVL SISLLSNSSS TVDIVEAQSK YGFWGWNLWR QPIGFIVFLI SSLAECERLP FDLPEAEEEL VAGYQTEYSG IKFGLFYVAS YLNLLVSSLF VTVLYLGGWN ISIPYIFVPE LFEINKAGRV FGTIIGIFIT LAKTYLFLFI SITTRWTLPR LRMDQLLNLG WKFLLPISLG NLLLTTSSQL LSL //