ID A0A271UD45_ECOLX Unreviewed; 265 AA. AC A0A271UD45; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 08-MAY-2019, entry version 6. DE RecName: Full=Protein MtfA {ECO:0000256|HAMAP-Rule:MF_01593}; DE AltName: Full=Mlc titration factor A {ECO:0000256|HAMAP-Rule:MF_01593}; GN Name=mtfA {ECO:0000256|HAMAP-Rule:MF_01593}; GN ORFNames=BIU72_12200 {ECO:0000313|EMBL:PAR03876.1}; OS Escherichia coli. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=562 {ECO:0000313|EMBL:PAR03876.1, ECO:0000313|Proteomes:UP000215625}; RN [1] {ECO:0000313|EMBL:PAR03876.1, ECO:0000313|Proteomes:UP000215625} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GMR-RB-634 {ECO:0000313|EMBL:PAR03876.1, RC ECO:0000313|Proteomes:UP000215625}; RA Saavedra S.Y., Diaz L., Wiesner M., Correa A., Arevalo S.A., Reyes J., RA Hidalgo A.M., De La Cadena E., Perenguez M., Montano L.A., Ardila J., RA Rios R., Ovalle M.V., Diaz P., Porras P., Villegas M.V., Arias C.A., RA Castaneda E., Duarte C.; RT "Genomic and Molecular Characterization of Clinical Isolates of RT Enterobacteriaceae Harboring mcr-1 in Colombia, 2002-2016."; RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the regulation of ptsG expression by binding CC and inactivating Mlc. {ECO:0000256|HAMAP-Rule:MF_01593}. CC -!- SUBUNIT: Interacts with Mlc. {ECO:0000256|HAMAP-Rule:MF_01593}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01593}. CC -!- SIMILARITY: Belongs to the MtfA family. {ECO:0000256|HAMAP- CC Rule:MF_01593, ECO:0000256|SAAS:SAAS00963153}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:PAR03876.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MVPO01000021; PAR03876.1; -; Genomic_DNA. DR RefSeq; WP_001362605.1; NZ_SHKF01000020.1. DR Proteomes; UP000215625; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro. DR Gene3D; 3.40.390.10; -; 1. DR HAMAP; MF_01593; MtfA; 1. DR InterPro; IPR024079; MetalloPept_cat_dom_sf. DR InterPro; IPR010384; MtfA_fam. DR PANTHER; PTHR30164; PTHR30164; 1. DR Pfam; PF06167; Peptidase_M90; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000215625}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01593}. SQ SEQUENCE 265 AA; 30309 MW; 198E36659BBCF8A5 CRC64; MIKWPWKVQE SAHQTALPWQ EALSIPLLTC LTEQEQSKLV TLAERFLQQK RLVPLQGFEL DSLRSCRIAL LFCLPVLELG LEWLDGFHEV LIYPAPFVVD DEWEDDIGLV HNQRIVQSGQ SWQQGPIVLN WLDIQDSFDA SGFNLIIHEV AHKLDTRNGD RASGVPFIPL REVAGWEHDL HAAMNNIQEE IELVGENAAS IDAYAASDPA ECFAVLSEYF FSAPELFAPR FPSLWQRFCQ FYQQDPLQRL HHANDTDSFS TTNVH //