ID A0A257CIP7_9BURK Unreviewed; 211 AA. AC A0A257CIP7; DT 20-DEC-2017, integrated into UniProtKB/TrEMBL. DT 20-DEC-2017, sequence version 1. DT 10-OCT-2018, entry version 5. DE RecName: Full=Uridine kinase {ECO:0000256|HAMAP-Rule:MF_00551, ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00847169}; DE EC=2.7.1.48 {ECO:0000256|HAMAP-Rule:MF_00551, ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00852590}; DE AltName: Full=Cytidine monophosphokinase {ECO:0000256|HAMAP-Rule:MF_00551}; DE AltName: Full=Uridine monophosphokinase {ECO:0000256|HAMAP-Rule:MF_00551}; GN Name=udk {ECO:0000256|HAMAP-Rule:MF_00551}; GN ORFNames=CFE43_20300 {ECO:0000313|EMBL:OYT88850.1}; OS Burkholderiales bacterium PBB3. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales. OX NCBI_TaxID=2015565 {ECO:0000313|EMBL:OYT88850.1, ECO:0000313|Proteomes:UP000216249}; RN [1] {ECO:0000313|EMBL:OYT88850.1, ECO:0000313|Proteomes:UP000216249} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PBB3 {ECO:0000313|EMBL:OYT88850.1}; RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., RA Hubert P., Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., RA Blanc G., Gontero B.; RT "A metagenomic investigation of the 'star' freshwater diatom RT Asterionella formosa and its bacterial cohort."; RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP. CC {ECO:0000256|HAMAP-Rule:MF_00551, ECO:0000256|RuleBase:RU003825, CC ECO:0000256|SAAS:SAAS00852610}. CC -!- CATALYTIC ACTIVITY: ATP + uridine = ADP + UMP. {ECO:0000256|HAMAP- CC Rule:MF_00551, ECO:0000256|RuleBase:RU003825, CC ECO:0000256|SAAS:SAAS00852616}. CC -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage CC pathway; CTP from cytidine: step 1/3. {ECO:0000256|HAMAP- CC Rule:MF_00551, ECO:0000256|RuleBase:RU003825, CC ECO:0000256|SAAS:SAAS00852620}. CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage CC pathway; UMP from uridine: step 1/1. {ECO:0000256|HAMAP- CC Rule:MF_00551, ECO:0000256|RuleBase:RU003825, CC ECO:0000256|SAAS:SAAS00852602}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00551, CC ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00847170}. CC -!- SIMILARITY: Belongs to the uridine kinase family. CC {ECO:0000256|HAMAP-Rule:MF_00551, ECO:0000256|RuleBase:RU003825, CC ECO:0000256|SAAS:SAAS00852607}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:OYT88850.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; NKIK01000057; OYT88850.1; -; Genomic_DNA. DR UniPathway; UPA00574; UER00637. DR UniPathway; UPA00579; UER00640. DR Proteomes; UP000216249; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. DR GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-UniRule. DR GO; GO:0044211; P:CTP salvage; IEA:UniProtKB-UniPathway. DR GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway. DR CDD; cd02023; UMPK; 1. DR HAMAP; MF_00551; Uridine_kinase; 1. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR006083; PRK/URK. DR InterPro; IPR000764; Uridine_kinase-like. DR InterPro; IPR026008; Uridine_kinase_. DR Pfam; PF00485; PRK; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00235; udk; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00551, KW ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00856990}; KW Complete proteome {ECO:0000313|Proteomes:UP000216249}; KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00551, KW ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00847174}; KW Kinase {ECO:0000256|HAMAP-Rule:MF_00551, KW ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00856988, KW ECO:0000313|EMBL:OYT88850.1}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00551, KW ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00856984}; KW Reference proteome {ECO:0000313|Proteomes:UP000216249}; KW Transferase {ECO:0000256|HAMAP-Rule:MF_00551, KW ECO:0000256|RuleBase:RU003825, ECO:0000256|SAAS:SAAS00856992}. FT DOMAIN 10 190 PRK. {ECO:0000259|Pfam:PF00485}. FT NP_BIND 15 22 ATP. {ECO:0000256|HAMAP-Rule:MF_00551}. SQ SEQUENCE 211 AA; 23659 MW; 5499F467D1C48DAD CRC64; MPKTKNKPFV IGVAGGSGSG KSTVTREVLA SIGPDMAAVV MQDDYYLDQT HMSPEDRRKT NYDHPDAFDW PLMAQHVRAL RNGEAIEMPE YDFAADNRSS KTITVNPAPV IVVEGLFALY DAKLRNMMSL KIYVDTASDV RFIRRLQRDI AERGRSTDSV IKQYLETVRP MHKQFIEPTK RNADVILPHG ANGPAVDIIT TKVISLIRDL E //