ID A0A221Q4S6_9MICC Unreviewed; 312 AA. AC A0A221Q4S6; DT 25-OCT-2017, integrated into UniProtKB/TrEMBL. DT 25-OCT-2017, sequence version 1. DT 28-JUN-2023, entry version 20. DE SubName: Full=LysR family transcriptional regulator {ECO:0000313|EMBL:ASN39371.1}; GN ORFNames=CGQ24_10340 {ECO:0000313|EMBL:ASN39371.1}; OS Arthrobacter sp. 7749. OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae; OC Arthrobacter. OX NCBI_TaxID=2020130 {ECO:0000313|EMBL:ASN39371.1, ECO:0000313|Proteomes:UP000199762}; RN [1] {ECO:0000313|EMBL:ASN39371.1, ECO:0000313|Proteomes:UP000199762} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=7749 {ECO:0000313|EMBL:ASN39371.1, RC ECO:0000313|Proteomes:UP000199762}; RA Sastre D.E., Santos L., Kagohara E., Andrade L.H.; RT "Draft Genome Sequence of a Psychrotrophic Arthrobacter sp. Strain 7749, RT Isolated from an Antarctic Marine Sediment with Applications in RT Enantioselective Alcohol Oxidation."; RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family. CC {ECO:0000256|ARBA:ARBA00009437}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP022462; ASN39371.1; -; Genomic_DNA. DR AlphaFoldDB; A0A221Q4S6; -. DR EnsemblBacteria; ASN39371; ASN39371; CGQ24_10340. DR Proteomes; UP000199762; Chromosome. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR CDD; cd08423; PBP2_LTTR_like_6; 1. DR Gene3D; 3.40.190.290; -; 1. DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1. DR InterPro; IPR005119; LysR_subst-bd. DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1. DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1. DR Pfam; PF00126; HTH_1; 1. DR Pfam; PF03466; LysR_substrate; 1. DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1. DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1. DR PROSITE; PS50931; HTH_LYSR; 1. PE 3: Inferred from homology; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00253}; KW Reference proteome {ECO:0000313|Proteomes:UP000199762}; KW Transcription {ECO:0000256|PROSITE-ProRule:PRU00253}; KW Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00253}. FT DOMAIN 10..67 FT /note="HTH lysR-type" FT /evidence="ECO:0000259|PROSITE:PS50931" FT DNA_BIND 27..46 FT /note="H-T-H motif" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00253" SQ SEQUENCE 312 AA; 34518 MW; CCDB46603F820F80 CRC64; MLNDDNQDLF DIRRLALLVE VVEQGSITAA ADLMMYTPSA VSQQMRKLEQ EVGQPLLNRR SRGVAPTEAG QLLAGHARKI IGQMRAAQSD LDQIAGLGRG SLTVGTFPTL AGSFLPVVIR AFKKRYPAIG LSVRSARFDE LVSDLEAGVT GLCLLWDYPW NRFSDDSIRV TEVFQESTVI LVARGHRLAD RDEVRMEELR TESWIVRAEA HPVVEVLQRS AHDAGFEPTI GFLANDYQEA QAMVSVGMGV AMVPKTAVAL QHPDVRVIGL GDAAPMRRVF LAQRQDKIYA PAEVAFQSTL LEIARDHHED YL //