ID A0A212MG01_ZYGBA Unreviewed; 928 AA. AC A0A212MG01; DT 22-NOV-2017, integrated into UniProtKB/TrEMBL. DT 22-NOV-2017, sequence version 1. DT 19-JAN-2022, entry version 12. DE SubName: Full=Related to Manganese resistance protein MNR2 {ECO:0000313|EMBL:SJM88603.1}; GN ORFNames=ZBIST_4792 {ECO:0000313|EMBL:SJM88603.1}; OS Zygosaccharomyces bailii. OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces. OX NCBI_TaxID=4954 {ECO:0000313|EMBL:SJM88603.1, ECO:0000313|Proteomes:UP000196771}; RN [1] {ECO:0000313|EMBL:SJM88603.1, ECO:0000313|Proteomes:UP000196771} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IST302 {ECO:0000313|EMBL:SJM88603.1, RC ECO:0000313|Proteomes:UP000196771}; RA Peterson S.W.; RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) CC family. {ECO:0000256|ARBA:ARBA00009765}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FUGC01000026; SJM88603.1; -; Genomic_DNA. DR Proteomes; UP000196771; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro. DR CDD; cd12829; Alr1p-like; 1. DR InterPro; IPR044089; Alr1-like. DR InterPro; IPR045861; CorA_cytoplasmic_dom. DR InterPro; IPR045863; CorA_TM1_TM2. DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB. DR Pfam; PF01544; CorA; 2. DR SUPFAM; SSF143865; SSF143865; 1. DR SUPFAM; SSF144083; SSF144083; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 866..889 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 901..922 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REGION 1..126 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 197..234 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 537..568 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 582..618 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 704..728 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..22 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 23..50 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 79..94 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 101..117 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 198..234 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 537..563 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 590..618 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 928 AA; 106419 MW; DD54147D6AB898A9 CRC64; MTDNTKHESQ PLLSPKTTRS SSDGSKSFEH DLLHHRKQHP NKDKPKVGSG LRSERGLTPL TDFDQADSWG LLHEADDSTS SKVATDKDNF IDHRPTLENM AGRSKSISKS VSTTSMSHHH KSSEHDNHDL FRWDDASERA LLAKMSPSEL EDWAKRDRLR SLHHGSRLKR STGVRRRSTM GNDVVIDVDE LMEHVKGHSS SIKSTPSVST NKSGSSQGDG YNSRPSSRRS SNNSSLDDVC LYLEHENSPE SKVWPDVYVL DDFCKEETER LRRQAVEDAE EFHFQYDDED EGDEESGNNN NDGIFFSKPI VTSIDVPELG NKKVNEAEQL KRGRLRPKKL APWHLRRKAL MSSSYQTLKD HTKTEDDSNM RDNFLVGRNI QYPPHIVNNN PEHFRFTYFR VDLDSTVHSP TISGLLQPGQ KFEELFVASV YTDLASKRHS GTPSGSRADI LSNHKGSNRR LNSMAATTSE LENVQPFWLD VLNPTEEEMK VLSKAFGIHP LTTEDIFLGE AREKVELFRD YYLVCFRSFD IVAERHTRKK KEKHQFETNS PVTERESLHR SQHSTRRPSG WLQSLFHRRR RSSATRTLAN SSERRRRSEL EKEEKQKYKR KSGDRYKPRE GELEPLNVYI IVFKTGVLTF HFAPTPHPIN VRRRARLLKD YLNVSADWIA YALIDDITDA FAPMIELIED EVYDIEDAIL RMHSSDDSSE EVSDDSDNPD SDNESFPFDR VSRRSAVSWG SRSESTRSSR SQTTGESTFN ANLIGWKKKG DMLRRIGECR KRVMSILRLL GSKADVIKGF AKRCNERWDV APRSEIGMYL GDIQDHIITM FSALNHYEKL LSRSHSNYLA QINIDMTKVN NDMNDVLGKI TILGTVVLPM NVMTGLWGMN VLVPGQNRPT LTWFWGIFAT MVIMAYTAYM YTKRRFGF //