ID A0A212D6A4_CEREH Unreviewed; 89 AA. AC A0A212D6A4; DT 27-SEP-2017, integrated into UniProtKB/TrEMBL. DT 27-SEP-2017, sequence version 1. DT 07-OCT-2020, entry version 8. DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982}; DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982}; GN ORFNames=Celaphus_00017256 {ECO:0000313|EMBL:OWK13771.1}; OS Cervus elaphus hippelaphus (European red deer). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae; OC Cervinae; Cervus. OX NCBI_TaxID=46360 {ECO:0000313|EMBL:OWK13771.1, ECO:0000313|Proteomes:UP000242450}; RN [1] {ECO:0000313|Proteomes:UP000242450} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=29294181; RA Bana N.A., Nyiri A., Nagy J., Frank K., Nagy T., Steger V., Schiller M., RA Lakatos P., Sugar L., Horn P., Barta E., Orosz L.; RT "The red deer Cervus elaphus genome CerEla1.0: sequencing, annotating, RT genes, and chromosomes."; RL Mol. Genet. Genomics 293:665-684(2018). CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide; CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6; CC Evidence={ECO:0000256|ARBA:ARBA00000457}; CC -!- SIMILARITY: Belongs to the ADP-ribosyl cyclase family. CC {ECO:0000256|ARBA:ARBA00005406}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:OWK13771.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MKHE01000006; OWK13771.1; -; Genomic_DNA. DR Proteomes; UP000242450; Chromosome 6. DR GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:UniProtKB-EC. DR GO; GO:0061809; F:NAD+ nucleotidase, cyclic ADP-ribose generating; IEA:UniProtKB-EC. DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW. DR InterPro; IPR003193; ADP-ribosyl_cyclase. DR PANTHER; PTHR10912; PTHR10912; 1. DR Pfam; PF02267; Rib_hydrolayse; 1. PE 3: Inferred from homology; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Reference proteome {ECO:0000313|Proteomes:UP000242450}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT REGION 1..21 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 89 AA; 10106 MW; A5BAAA77A9959F80 CRC64; MYTSGLHVES GLDYQSCPTS EDCENNPVDS FWRSASVQVS TRATVNQGKR HFGQIFRYRE SLELSRGWLP TKEFFFLSLL PASGSPRLT //