ID A0A1Y2DZC6_9PEZI Unreviewed; 1108 AA. AC A0A1Y2DZC6; DT 30-AUG-2017, integrated into UniProtKB/TrEMBL. DT 30-AUG-2017, sequence version 1. DT 05-JUN-2019, entry version 7. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ORY64454.1}; GN ORFNames=BCR38DRAFT_343583 {ECO:0000313|EMBL:ORY64454.1}; OS Pseudomassariella vexata. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Xylariomycetidae; Xylariales; Pseudomassariaceae; OC Pseudomassariella. OX NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY64454.1, ECO:0000313|Proteomes:UP000193689}; RN [1] {ECO:0000313|EMBL:ORY64454.1, ECO:0000313|Proteomes:UP000193689} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY64454.1, RC ECO:0000313|Proteomes:UP000193689}; RG DOE Joint Genome Institute; RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A., RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B., RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., RA Culley D., Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., RA Spatafora J.W., Visel A., Grigoriev I.V.; RT "Pervasive Adenine N6-methylation of Active Genes in Fungi."; RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L- CC cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin- CC conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor CC protein]-L-lysine.; EC=2.3.2.26; CC Evidence={ECO:0000256|SAAS:SAAS00628607}; CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:ORY64454.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MCFJ01000007; ORY64454.1; -; Genomic_DNA. DR OrthoDB; 339404at2759; -. DR Proteomes; UP000193689; Unassembled WGS sequence. DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro. DR CDD; cd00078; HECTc; 1. DR InterPro; IPR000569; HECT_dom. DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase. DR Pfam; PF00632; HECT; 1. DR SMART; SM00119; HECTc; 1. DR SUPFAM; SSF56204; SSF56204; 1. DR PROSITE; PS50237; HECT; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000193689}; KW Reference proteome {ECO:0000313|Proteomes:UP000193689}; KW Transferase {ECO:0000256|SAAS:SAAS00628615}; KW Ubl conjugation pathway {ECO:0000256|PROSITE-ProRule:PRU00104, KW ECO:0000256|SAAS:SAAS00593691}. FT DOMAIN 759 1108 HECT. {ECO:0000259|PROSITE:PS50237}. FT REGION 1 99 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT REGION 130 149 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT REGION 171 192 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT REGION 234 265 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT REGION 300 337 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT REGION 573 592 Disordered. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT COMPBIAS 15 31 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT COMPBIAS 56 75 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT COMPBIAS 131 149 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT COMPBIAS 235 252 Polar. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT COMPBIAS 304 321 Polar. {ECO:0000256|MobiDB-lite: FT A0A1Y2DZC6}. FT ACT_SITE 1076 1076 Glycyl thioester intermediate. FT {ECO:0000256|PROSITE-ProRule:PRU00104}. SQ SEQUENCE 1108 AA; 124881 MW; 091CC4292DDAE994 CRC64; MDVFRNPHGQ LQHHAESSST DDDDIRFSKP KPKSRPARHS RSMSHPITSL FSKKKKPASD GVDDDSTDDD TTHARGQLGL RTSMAPPGPR RRSADSVKGN CMTCGSQVSW PKEVDAFRCS ICVTINDLKP FNPPRRDEKG SEPPRPISLE HTKFLVREGL RCALNSFLVG RAPKDRNGTS DAGPSGPLSR VAGDYFSQKQ DRPISIHRSP PVLIPSPVFD GHTEVSFEMN PLRQLAGPSR SNSTSYPDAR SSGLPSKPQK REPVGIDGCR IFKPLEDYLA TSFNSYACIN ASFVARRKSF SSRPVGAQPR TRRQSFKSAP IDTPRNRRGS RSDPVNTDTL VSELDAKMLL VGDIAENGSW WTGGQEIQPL RAQSWRLNEP QPIANARSPQ IDWKEATAWY HSVINAGESW TDVYGELVQK DPTKTLSELD GQNFEQLVLA AQEHLQRVLL KCTENFLKRP GRLLKEPQDS RFLLLFLANP LLLHGHKTYA GVCQHLRKEP RAPEDAYTVG RHSVIIKRIL GILSHLPDPC HHHFVGWFSR LPEHIFLQIK DLVSSFVTYR LVRANEKRSE PKVDLTGGLI PQMPSNRSSN NAASLHAALG TSQRSNKRKP VELKKTTYGD DWQMKAGAQV MALVFAANNV THVRRNEVSV RHAHGHLLAT SDFYNTLLDT MDFRADFEEW ESKKSKFSFC HYPFFLSIWT KIRILEFDAK RQMAHKAHQA LVDSVLTHRN FAQYISLRVR RDCLVEDSLR QVSQVVGSGS EEIKKGLRIE FDGEEGVDAG GLRKEWFLLL VREVFNPDHG LFVFDEDSQH CYFNPHTFET SDQYFLVGVV LGLAIYHSTI LDIALPPFAF RKLLAAAPAP STGITGLLRP PMTYSLSDLR EYRPRLAHGL KQLLEFEGDV ESTFCRDFVI ETEKYGTTIR TPLCPGGENM QVTNNNRHKF VELYVRYLLD TSVSRQFEPF KRGFFTVCAG NALSLFRPEE IELLVRGSDE PLDIATLRAV ATYTNWEPDK SSEPELEPTV DWFWKSFAAA SPADQRRLLS FITGSDRIPA MGAASLVIKI NCLGDDIGRY PTAQTCFNAL NLFRYRLQES LEVKLWGAVR ESEGFGLR //