ID A0A1Y1I1U1_KLENI Unreviewed; 175 AA. AC A0A1Y1I1U1; DT 30-AUG-2017, integrated into UniProtKB/TrEMBL. DT 30-AUG-2017, sequence version 1. DT 07-OCT-2020, entry version 10. DE RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1 {ECO:0000256|ARBA:ARBA00013306, ECO:0000256|PIRNR:PIRNR008716}; GN ORFNames=KFL_001690100 {ECO:0000313|EMBL:GAQ83932.1}; OS Klebsormidium nitens (Green alga) (Ulothrix nitens). OC Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae; OC Klebsormidiales; Klebsormidiaceae; Klebsormidium. OX NCBI_TaxID=105231 {ECO:0000313|EMBL:GAQ83932.1, ECO:0000313|Proteomes:UP000054558}; RN [1] {ECO:0000313|EMBL:GAQ83932.1, ECO:0000313|Proteomes:UP000054558} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NIES-2285 {ECO:0000313|EMBL:GAQ83932.1, RC ECO:0000313|Proteomes:UP000054558}; RX PubMed=24865297; DOI=10.1038/ncomms4978; RA Hori K., Maruyama F., Fujisawa T., Togashi T., Yamamoto N., Seo M., RA Sato S., Yamada T., Mori H., Tajima N., Moriyama T., Ikeuchi M., RA Watanabe M., Wada H., Kobayashi K., Saito M., Masuda T., RA Sasaki-Sekimoto Y., Mashiguchi K., Awai K., Shimojima M., Masuda S., RA Iwai M., Nobusawa T., Narise T., Kondo S., Saito H., Sato R., Murakawa M., RA Ihara Y., Oshima-Yamada Y., Ohtaka K., Satoh M., Sonobe K., Ishii M., RA Ohtani R., Kanamori-Sato M., Honoki R., Miyazaki D., Mochizuki H., RA Umetsu J., Higashi K., Shibata D., Kamiya Y., Sato N., Nakamura Y., RA Tabata S., Ida S., Kurokawa K., Ohta H.; RT "Klebsormidium flaccidum genome reveals primary factors for plant RT terrestrial adaptation."; RL Nat. Commun. 5:3978-3978(2014). CC -!- FUNCTION: E1-like enzyme which specifically catalyzes the second step CC in ufmylation. Ufmylation is involved in reticulophagy (also called ER- CC phagy) induced in response to endoplasmic reticulum stress. CC {ECO:0000256|PIRNR:PIRNR008716}. CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1 CC subfamily. {ECO:0000256|ARBA:ARBA00008451, CC ECO:0000256|PIRNR:PIRNR008716}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DF237118; GAQ83932.1; -; Genomic_DNA. DR OrthoDB; 1339876at2759; -. DR Proteomes; UP000054558; Unassembled WGS sequence. DR Gene3D; 3.10.110.10; -; 1. DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD. DR InterPro; IPR014806; Ufc1. DR PANTHER; PTHR12921; PTHR12921; 1. DR Pfam; PF08694; UFC1; 1. DR PIRSF; PIRSF008716; DUF1782; 1. DR SUPFAM; SSF54495; SSF54495; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000054558}; KW Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR008716}. FT ACT_SITE 119 FT /note="Glycyl thioester intermediate" FT /evidence="ECO:0000256|PIRSR:PIRSR008716-1" SQ SEQUENCE 175 AA; 19821 MW; EDAD7D916DCBC6F7 CRC64; MEGWDTSTKA VVQKIPLLTV KAGPRDGEDW KKRLKEEYQA LIAYMQMNKA NDNDWFRISA ANPEGTKWKG KCWYIHNLLK YEFDLQFDIP ATYPATAPEL ELPELDGKTA KMYRGGKICL TIHFKPLWAK NVPHFGVAHA LCLGMGPWLA AEIPHLVETG MIQHKDNTAK ATPPT //