ID A0A1X9YHF1_9SPHN Unreviewed; 461 AA. AC A0A1X9YHF1; DT 30-AUG-2017, integrated into UniProtKB/TrEMBL. DT 30-AUG-2017, sequence version 1. DT 24-JAN-2024, entry version 19. DE SubName: Full=Glutamine synthetase {ECO:0000313|EMBL:ARS28140.1}; GN ORFNames=KC8_12735 {ECO:0000313|EMBL:ARS28140.1}; OS Sphingomonas sp. KC8. OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales; OC Sphingomonadaceae; Sphingomonas. OX NCBI_TaxID=1030157 {ECO:0000313|EMBL:ARS28140.1, ECO:0000313|Proteomes:UP000194475}; RN [1] {ECO:0000313|EMBL:ARS28140.1, ECO:0000313|Proteomes:UP000194475} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KC8 {ECO:0000313|EMBL:ARS28140.1}; RA Chen Y.-L., Yu C.-P., Hu A., Lee T.-H., Yang F.-C., Ismail W., Wang P.-H., RA Wang C.-H., Goh K.-S., Shih C.-J., Chiang Y.-R.; RT "Bacteria use an extradiol dioxygenase-mediated pathway to degrade natural RT estrogens in aquatic ecosystems."; RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|ARBA:ARBA00001946}; CC -!- SIMILARITY: Belongs to the glutamine synthetase family. CC {ECO:0000256|PROSITE-ProRule:PRU01331, ECO:0000256|RuleBase:RU000384}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP016306; ARS28140.1; -; Genomic_DNA. DR RefSeq; WP_010123092.1; NZ_CP016306.1. DR AlphaFoldDB; A0A1X9YHF1; -. DR STRING; 1030157.GCA_000214335_03804; -. DR KEGG; spkc:KC8_12735; -. DR eggNOG; COG0174; Bacteria. DR OrthoDB; 9807095at2; -. DR Proteomes; UP000194475; Chromosome. DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro. DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro. DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1. DR InterPro; IPR036651; Gln_synt_N_sf. DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom. DR InterPro; IPR008146; Gln_synth_cat_dom. DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1. DR PANTHER; PTHR43785:SF12; TYPE-1 GLUTAMINE SYNTHETASE 2; 1. DR Pfam; PF00120; Gln-synt_C; 1. DR SMART; SM01230; Gln-synt_C; 1. DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1. DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1. DR PROSITE; PS51987; GS_CATALYTIC; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000194475}. FT DOMAIN 127..461 FT /note="GS catalytic" FT /evidence="ECO:0000259|PROSITE:PS51987" SQ SEQUENCE 461 AA; 49552 MW; 23351EC0B952E1B1 CRC64; MTKAAIPAGF VADPAEGRAF LAAHPHIALF DVFFTGLSGV PRGKRLRRHE VEAVYDYGRF LPGSIQVVDI TGRDCEDTGL VWEDGDADRR ARPVPGGIVP APWLGDDVGQ LMCSLHELDG AVCELDPRAI LSRVIDRFTA DGLTPVVACE LEFYLVDGRR GRDGSVRLPR GMATATEVYG LPQVEEASPF LRDLWAACDA QGIPLEGVIS ECAPGQLELT LKHKGDALRA ADDAVAYKRA AKGVAKNHGC DVTFMAKPWA DRAGSGLHLH VSLADGQGLN LFAADDVAGT PMLRHAIGGM GALLAESMAI FAPNMNSYRR FKANSYAPTA PTWGVNNRTV ALRVPAGLPH TRHIEHRVAG ADANPYLAVA ALLAAVHHGI THKIDPGPAV TGDGYAAAAA AGTSLPTNWF DAVRLFEQSA VLRDYLGDRT VDMFTIVKRT EQTRFMEQVS ALDHDWYLHN A //