ID A0A1X9TYT7_PHODD Unreviewed; 436 AA. AC A0A1X9TYT7; DT 30-AUG-2017, integrated into UniProtKB/TrEMBL. DT 30-AUG-2017, sequence version 1. DT 22-FEB-2023, entry version 17. DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493}; DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493}; GN ORFNames=CAY62_01860 {ECO:0000313|EMBL:ARR48434.1}, CAY62_02555 GN {ECO:0000313|EMBL:ARR48547.1}, CAY62_04010 GN {ECO:0000313|EMBL:ARR48817.1}, CAY62_08190 GN {ECO:0000313|EMBL:ARR49557.1}, CAY62_09105 GN {ECO:0000313|EMBL:ARR49713.1}, CAY62_11465 GN {ECO:0000313|EMBL:ARR50094.1}, CAY62_13275 GN {ECO:0000313|EMBL:ARR50390.1}, CAY62_15040 GN {ECO:0000313|EMBL:ARR50811.1}; OS Photobacterium damselae subsp. damselae (Listonella damsela). OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; OC Photobacterium. OX NCBI_TaxID=85581 {ECO:0000313|EMBL:ARR48547.1, ECO:0000313|Proteomes:UP000194333}; RN [1] {ECO:0000313|EMBL:ARR48547.1, ECO:0000313|Proteomes:UP000194333} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KC-Na-1 {ECO:0000313|EMBL:ARR48547.1}; RA Kim J.H., Lee K.; RT "Complete genome sequence of Photobacterium damselae subsp. damselae KC-Na- RT 1 isolated from Neophocaena asiaeorientalis in Korea."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, CC ChEBI:CHEBI:173112; EC=2.7.7.49; CC Evidence={ECO:0000256|ARBA:ARBA00024557}; CC -!- SIMILARITY: Belongs to the bacterial reverse transcriptase family. CC {ECO:0000256|ARBA:ARBA00034120}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP021151; ARR48434.1; -; Genomic_DNA. DR EMBL; CP021151; ARR48547.1; -; Genomic_DNA. DR EMBL; CP021151; ARR48817.1; -; Genomic_DNA. DR EMBL; CP021151; ARR49557.1; -; Genomic_DNA. DR EMBL; CP021151; ARR49713.1; -; Genomic_DNA. DR EMBL; CP021151; ARR50094.1; -; Genomic_DNA. DR EMBL; CP021151; ARR50390.1; -; Genomic_DNA. DR EMBL; CP021152; ARR50811.1; -; Genomic_DNA. DR AlphaFoldDB; A0A1X9TYT7; -. DR EnsemblBacteria; ARR48434; ARR48434; CAY62_01860. DR EnsemblBacteria; ARR48547; ARR48547; CAY62_02555. DR EnsemblBacteria; ARR48817; ARR48817; CAY62_04010. DR EnsemblBacteria; ARR49557; ARR49557; CAY62_08190. DR EnsemblBacteria; ARR49713; ARR49713; CAY62_09105. DR EnsemblBacteria; ARR50094; ARR50094; CAY62_11465. DR EnsemblBacteria; ARR50390; ARR50390; CAY62_13275. DR EnsemblBacteria; ARR50811; ARR50811; CAY62_15040. DR KEGG; pds:CAY62_01860; -. DR KEGG; pds:CAY62_02555; -. DR KEGG; pds:CAY62_04010; -. DR KEGG; pds:CAY62_08190; -. DR KEGG; pds:CAY62_09105; -. DR KEGG; pds:CAY62_11465; -. DR KEGG; pds:CAY62_13275; -. DR KEGG; pds:CAY62_15040; -. DR Proteomes; UP000194333; Chromosome i. DR Proteomes; UP000194333; Chromosome ii. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW. DR CDD; cd01651; RT_G2_intron; 1. DR Gene3D; 3.30.70.270; -; 1. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR030931; Group_II_RT_mat. DR InterPro; IPR013597; Mat_intron_G2. DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase. DR InterPro; IPR000123; Reverse_transcriptase_msDNA. DR InterPro; IPR000477; RT_dom. DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1. DR PANTHER; PTHR34047:SF9; PROTEIN YKFC; 1. DR Pfam; PF08388; GIIM; 1. DR Pfam; PF00078; RVT_1; 1. DR PRINTS; PR00866; RNADNAPOLMS. DR SUPFAM; SSF56672; DNA/RNA polymerases; 1. DR TIGRFAMs; TIGR04416; group_II_RT_mat; 1. DR PROSITE; PS50878; RT_POL; 1. PE 3: Inferred from homology; KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118}; KW Nucleotidyltransferase {ECO:0000313|EMBL:ARR48547.1}; KW RNA-directed DNA polymerase {ECO:0000313|EMBL:ARR48547.1}; KW Transferase {ECO:0000313|EMBL:ARR48547.1}. FT DOMAIN 53..279 FT /note="Reverse transcriptase" FT /evidence="ECO:0000259|PROSITE:PS50878" SQ SEQUENCE 436 AA; 50370 MW; 7652A551979915B4 CRC64; MTSTSLMEQI CSSTNLNQAL RRVKKNKGCA GVDKLDINAT IFQLRQASNG QLLRQSLLDG SYQPQPVLGV EIPKPSGGVR QLGIPTVLDR IVQQAITSTL SDIYEPKFSN SSYGFRPNRS AHHALAAASR YIRDGRGYVV DIDLAKYFDT VNHDRLMHRL SQDIVDKRVL KLIRSYLQAG IMRNGMVEQR QRGTPQGGPL SPLLSNIVLD ELDKELEHRG HKFCRYADDC QIYVSSEEAA HRVKESITKF LEQKLKLTVN REKSAATRVT ERTYLGHRFQ IDGTIQISKP AQTQMKKRVR QITKRNRGRE LKEVITELTQ YLRGWQHYFK LVMRKSSMQQ LDSWIRRRLR CYRLKQRKRK YSIAMWLQQQ GVTERNAWKL AMSDKGWWCL AQTPQMHHAM PIKWFKELGL YSLGDGYESL KIYSEPPYAI HACTVV //