ID A0A1X9TTR7_9LACO Unreviewed; 223 AA. AC A0A1X9TTR7; DT 30-AUG-2017, integrated into UniProtKB/TrEMBL. DT 30-AUG-2017, sequence version 1. DT 10-FEB-2021, entry version 10. DE SubName: Full=Rhomboid family intramembrane serine protease {ECO:0000313|EMBL:ARR37034.1}; GN ORFNames=B9N98_01750 {ECO:0000313|EMBL:ARR37034.1}, LDE01_12230 GN {ECO:0000313|EMBL:BBL27926.1}; OS Lactobacillus delbrueckii subsp. delbrueckii. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lactobacillus. OX NCBI_TaxID=83684 {ECO:0000313|EMBL:ARR37034.1, ECO:0000313|Proteomes:UP000194365}; RN [1] {ECO:0000313|EMBL:ARR37034.1, ECO:0000313|Proteomes:UP000194365} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=TUA4408L {ECO:0000313|EMBL:ARR37034.1}; RA Hebert E.M., Saavedra L., Molina D., Albarracin L., Egusa S., Tanaka N., RA Okada S., Villena J., Kitazawa H.; RT "Genome sequencing of Lactobacillus delbrueckii TUA4408L."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:BBL27926.1, ECO:0000313|Proteomes:UP000319966} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NBRC 3202 {ECO:0000313|EMBL:BBL27926.1, RC ECO:0000313|Proteomes:UP000319966}; RA Miura T., Furukawa M., Shimamura M., Ohyama Y., Yamazoe A., Kawasaki H.; RT "Complete genome sequence of Lactobacillus delbrueckii subsp. delbrueckii RT NBRC 3202."; RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP021136; ARR37034.1; -; Genomic_DNA. DR EMBL; AP019750; BBL27926.1; -; Genomic_DNA. DR RefSeq; WP_025895840.1; NZ_LHPL01000076.1. DR GeneID; 57118444; -. DR Proteomes; UP000194365; Chromosome. DR Proteomes; UP000319966; Chromosome. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. DR Gene3D; 1.20.1540.10; -; 1. DR InterPro; IPR002610; Peptidase_S54_rhomboid. DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom. DR InterPro; IPR035952; Rhomboid-like_sf. DR PANTHER; PTHR22936; PTHR22936; 1. DR Pfam; PF01694; Rhomboid; 1. PE 4: Predicted; KW Hydrolase {ECO:0000313|EMBL:ARR37034.1}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Protease {ECO:0000313|EMBL:ARR37034.1}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 56..80 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 92..110 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 116..136 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 143..164 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 170..189 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 201..221 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 50..188 FT /note="Rhomboid" FT /evidence="ECO:0000259|Pfam:PF01694" SQ SEQUENCE 223 AA; 23893 MW; 8E4DD192FB1FCB14 CRC64; MNNLRRNYMT TALVVVLFAV FLVETFMGGS ESTSVLLKMG AMFNPAVVME GQWWRLFTAQ FLHIGIMHIA SNAIMIYYIG QYAEPVFGHW RFLLIYLLSG VGGSLLTLAF GNDQAISAGA STALFGLFGA MTCAGFKDKD NTLLSFLGRQ ALALAVINLV LDVFMPDVDI LGHLGGLITG ALLAVILGDA TYKGYGKGGR LLAAAGLIVY VVLILRLGMA VTV //